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4-Bromo-5-(trifluoromethyl)-1H-indazole
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4-Bromo-5-(trifluoromethyl)-1H-indazole
Supplier:
AMBEED, INC
Description:
4-Chloro-3,5-bis(trifluoromethyl)benzoic acid, Purity: 95%, CAS number: 773108-93-3, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Supplier:
AOB CHEM USA
Description:
1,4-Dibromo-2-chloro-5-(trifluoromethyl)benzene ≥97%
Supplier:
AMBEED, INC
Description:
Methyl 5-(trifluoromethyl)pyrazole-3-carboxylate, Purity: 97%, CAS Number: 6833-82-5, Appearance: OFF-WHITE CRYSTAL, Storage: Sealed in dry, 2-8 C, Size: 1g
Catalog Number:
(102840-572)
Supplier:
Matrix Scientific
Description:
Methyl-3-amino-2-(trifluoromethyl)propionate ≥97%
Supplier:
AMBEED, INC
Description:
6-(4-(Trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine 98+%
Supplier:
AOB CHEM USA
Description:
(5-cCloro-2-fluoro-4-(trifluoromethyl)phenyl)(methyl)sulfane ≥97%
Catalog Number:
(10300-338)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Supplier:
Matrix Scientific
Description:
MF=C12H5Cl2F3O2 MW=309.07 Cas=175276-61-6 MDL=MFCD00275554 ,250Mg
Supplier:
AOB CHEM USA
Description:
4-Benzyloxy-2-(trifluoromethyl)phenylboronic acid ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054854-500MG , MDL Number: MFCD16140326
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051867-500MG , MDL Number: MFCD13561838
Supplier:
APOLLO SCIENTIFIC
Description:
2-Chloro-6-(trifluoromethyl)phenylacetonitrile 97%
Catalog Number:
(102520-198)
Supplier:
Matrix Scientific
Description:
MF=C14H8F6 MW=290.21 CAS=567-15-7 MDL=MFCD09836618 1G
Supplier:
Matrix Scientific
Description:
MF=C8H6F4O MW=194.13 Cas=152211-15-9 MDL=MFCD00061168 1G
Catalog Number:
(77619-792)
Supplier:
AMBEED, INC
Description:
4-(Trifluoromethyl)benzene-1-sulfonyl fluoride ≥95%
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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