4-Bromo-2,6-difluorophenol
Catalog Number:
(AG8710-1924)
Supplier:
AGILENT TECHNOLOGIES, INC (CSD)
Description:
A full range of supplies for pump valves, including inlet valves, outlet valves, and check valves.
Supplier:
AMBEED, INC
Description:
N2-(4-(1H-Benzo[d]imidazol-2-yl)phenyl)-N4-(4-fluorophenyl)-6-morpholino-1,3,5-triazine-2,4-diamine, Purity: 97%, CAS Number: 1807988-47-1, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 1MG
Catalog Number:
(10347-100)
Supplier:
Bioss
Description:
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Supplier:
AMBEED, INC
Description:
2,4-Dichloro-1-(chloromethyl)benzene, Purity: 98%, CAS Number: 94-99-5, Appearance: Form: liquid / Colour: Colorless - Almost colorless, Storage: Inert atmosphere, Room Temperature, Size: 25g
Supplier:
Akro-Mils
Description:
AkroBins are the industry-leading hanging and stacking plastic storage bin.
Catalog Number:
(10347-104)
Supplier:
Bioss
Description:
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Supplier:
AMBEED, INC
Description:
(2,2-Dichlorocyclopropyl)benzene, Purity: 97%, CAS Number: 2415-80-7, Appearance: Very pale yellow to Pale yellow to Yellow-brown Liquid, Storage: Sealed in dry, Room Temperature, Size: 5g
Catalog Number:
(77691-785)
Supplier:
LGC STANDARDS
Description:
ASTM Method D3606 Benzene in Gasoline Kit with IS in Isooctane, Dr. Ehrenstorfer, LGC Standards
Catalog Number:
(77692-693)
Supplier:
LGC STANDARDS
Description:
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione (Clobetasol), Mikromol, LGC Standards
Supplier:
AMBEED, INC
Description:
1-Bromo-3-methyl-5-(trifluoromethyl)benzene, Purity: 98%, CAS Number: 86845-28-5, Appearance: Colorless to Pale-yellow to Yellow-brown Liquid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Supplier:
AMBEED, INC
Description:
(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene, Purity: 98%, CAS Number: 22255-22-7, Appearance: Form: Crystal - Powder/Colour: White - Slightly pale yellow, Storage: Sealed in dry, 2-8 C, Size: 5g
Catalog Number:
(10347-098)
Supplier:
Bioss
Description:
Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Supplier:
National Marker
Description:
Alert employees and guests to smoking policies within your facility.
Supplier:
National Marker
Description:
Signs are the perfect way to alert your employees and guests when a hazard is present in your facility.
Catalog Number:
(10756-848)
Supplier:
Biolegend
Description:
Brilliant Violet 711™ anti-mouse CD62L [MEL-14]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC; Size: 50 μg
Catalog Number:
(10348-686)
Supplier:
Bioss
Description:
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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