3,5-Bis(4-aminophenoxy)benzoic+acid
Catalog Number:
(75842-298)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Catalog Number:
(75844-112)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HI100 monoclonal antibody specifically reacts with human CD45RA, the 220 kDa isoform of the human leukocyte common antigen (LCA) found on 40-50% of the peripheral CD4+ T lymphocytes, half of the peripheral CD8+ T lymphocytes and some of the monocytes and B lymphocytes. The CD45RA antigen is expressed by naïve and activated T lymphocytes. The HI100 monoclonal antibody is used as a phenotypic marker to discriminate T lymphocytes subsets.
Catalog Number:
(75844-496)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.
Catalog Number:
(103292-622)
Supplier:
Novus Biologicals
Description:
The VISTA / B7-H5 / PD-1H Antibody (855328) [FITC] from Novus Biologicals is a mouse monoclonal antibody to VISTA / B7-H5 / PD-1H. This antibody reacts with human. The VISTA / B7-H5 / PD-1H Antibody (855328) [FITC] has been validated for the following applications: Flow Cytometry.
Catalog Number:
(75843-014)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions.
The 24F antibody is capable of blocking the co-stimulatory activity of CD86.
Catalog Number:
(75844-498)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.
Catalog Number:
(10766-046)
Supplier:
Prosci
Description:
The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
Catalog Number:
(10764-248)
Supplier:
Prosci
Description:
The OKT3 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Catalog Number:
(75842-160)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA-(1-6) molecules with integrin alpha-(1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.
Catalog Number:
(103392-236)
Supplier:
Novus Biologicals
Description:
The Rabbit anti-Hamster IgG (H+L) Secondary Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to IgG (H+L). This antibody reacts with hamster. The Rabbit anti-Hamster IgG (H+L) Secondary Antibody [FITC] has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103360-450)
Supplier:
Novus Biologicals
Description:
The TLR4 Antibody [FITC] from Novus Biologicals is a rabbit polyclonal antibody to TLR4. This antibody reacts with human, mouse. The TLR4 Antibody [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(103392-606)
Supplier:
Novus Biologicals
Description:
The Goat anti-Rat IgG (H+L) Secondary Antibody [FITC] from Novus Biologicals is a goat polyclonal antibody to IgG (H+L). This antibody reacts with rat. The Goat anti-Rat IgG (H+L) Secondary Antibody [FITC] has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(10430-512)
Supplier:
Bioss
Description:
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
Catalog Number:
(10764-152)
Supplier:
Prosci
Description:
The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin beta 2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.
Catalog Number:
(89358-426)
Supplier:
Genetex
Description:
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion. But it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock.
Catalog Number:
(10332-798)
Supplier:
Bioss
Description:
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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