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Catalog Number:
(75792-938)
Supplier:
Prosci
Description:
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
Supplier:
AMBEED, INC
Description:
1,1-Bis((2R,5R)-2,5-diethylphospholano)ferrocene(cyclooctadiene)rhodium(I), Purity: 98%, CAS Number: 162412-90-0, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(103287-770)
Supplier:
Novus Biologicals
Description:
The Siglec-11 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Siglec-11. This antibody reacts with human. The Siglec-11 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry-Paraffin.
Supplier:
Strem Chemicals Inc
Description:
CAS #: 350683-75-9. Size: 0.5g.
Supplier:
Strem Chemicals Inc
Description:
BINAP
Catalog Number:
(TCD1854-005G)
Supplier:
TCI America
Description:
CAS Number: 36437-30-6
MDL Number: MFCD00060051 Molecular Formula: C26H42Br2N2 Molecular Weight: 542.44 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(77682-686)
Supplier:
CREATIVE BIOMART INC
Description:
Recombinant HPV-11 antigen, GST-tagged.
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7791-11-9. Size: 10g.
Supplier:
AMBEED, INC
Description:
(4S,4'S)-2,2'-(Cyclopentane-1,1-diyl)bis(4-isopropyl-4,5-dihydrooxazole), Purity: 97%, CAS Number: 1379452-52-4, Appearance: Solid or Semi-solid or liquid, Storage: Inert atmosphere, 2-8 C, Size: 250mg
Catalog Number:
(102842-822)
Supplier:
Matrix Scientific
Description:
(((4-(Dimethylamino)phenyl)amino)methylene)methane-1,1-dicarbonitrile ≥95%
Catalog Number:
(102971-606)
Supplier:
Adipogen
Description:
Inflammatory caspases (also known as group I caspases) are encoded by three main genes in humans, caspase-1, caspase-4 and caspase-5 and three main genes in mouse, caspase-1, caspase-11 and caspase-12. Caspase-11 is the murine orthologue of human caspase-4 and -5. Murine caspase-11 is a poorly characterized member of the caspase-1 subfamily. Caspase-11-deficient embryonic fibroblasts are resistant to apoptosis induced by ectopic expression of caspase-1, suggesting that caspase-11 is an upstream activator of caspase-1. Unlike caspase-1, the expression of caspase-11 is LPS-inducible and it is reasonable to postulate that other members of the family are regulated at the transcriptional or translational level by extracellular stimuli. Recently caspase-11 has been shown to be required for activation of the Nlrp3 inflammasome upon E. coli, V. cholerae and C. rodentium infection. The upstream activators of caspase-11 are TLR4 and TRIF, that modulate enteropathogen-induced inflammasome activation by promoting caspase-11 expression and activation. Formation of ASC foci (specks), a measure of NLRP3/ASC complex formation, requires caspase-11 but not caspase-1 indicating that caspase-11 acts upstream of the NLRP3/ASC complex.
Supplier:
Matrix Scientific
Description:
3',4'-Dihydro-2'H-spiro[cyclopentane-1,1'-pyrrolo[1,2-a]pyrazine]
Catalog Number:
(102165-028)
Supplier:
Novus Biologicals
Description:
The Septin-11 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Septin-11. This antibody reacts with human, mouse. The Septin-11 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number:
(101924-808)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 062922-500MG , MDL Number: MFCD00469406
Supplier:
AMBEED, INC
Description:
1,1-Bis((2R,5R)-2,5-di-i-propylphospholano)ferrocene(cyclooctadiene)rhodium(I), Purity: 98%, CAS Number: 849773-96-2, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(100273-370)
Supplier:
Indofine Chemical Company
Description:
Lipid Research 2091-27-2 100mg 306.53 Room temperature. 99+%.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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