Text Search >
4-Hydroxycyclohexanecarboxylic+acid+(cis+and+trans+mixture)
Print…
You Searched For:
135,312 results were found
4-Hydroxycyclohexanecarboxylic+acid+(cis+and+trans+mixture)
Catalog Number:
(89145-514)
Supplier:
Enzo Life Sciences
Description:
Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506. Proteins that bind FK506 are termed FK506 Binding Proteins (FKBPs) and those that bind cyclosporin A are called cyclophilins (CyP).
Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signalling enzyme in T-cell activation, providing a possible mechanism of immunosuppression by CsA and FK506. Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins. Within the cyclophilin family, there are several different proteins which show a high degree of homology including CyPA, CyPB and CyPC. CyPA, also termed CyP-18, is the most abundant and ubiquitous cyclophilin found in all vertebrate tissues and is present in T-cells. 
Supplier:
MP Biomedicals
Description:
Storage: Store at Room Temperature (15-30 °C).
D-myo-Inositol is a component of membrane phospholipids, glycosylphophatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. It is a growth factor for animals as well as microorganisms. Myo-Inositol is the most abundant form of polyols that serves as a structural element of secondary messengers in eukaryotic cells. Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound, a sixfold alcohol (polyol) of cyclohexane. It exists in nine possible stereoisomers, of which the most prominent form, widely occurring in nature, is cis-1,2,3,5-trans-4,6-cyclohexanehexol, or myo-inositol (former name meso-inositol). Inositol is a carbohydrate, though not a classical sugar. It has a taste which has been assayed at half the sweetness of table sugar. Used as a lipotropic agent. A component of membrane phospholipids, glycosylphosphatidylinositol anchors that bind glycoproteins to cell membranes, and inositol phosphate second messengers. In addition, inositol serves as an important component of the structural lipids phosphatidylinositol (PI) and its various phosphates, the phosphatidylinositol phosphate (PIP) lipids.
Catalog Number:
(PAL5511)
Supplier:
Promega Corporation
Description:
Amino Acid Mixture, Complete, is an aqueous solution containing 1mM each of the 20 essential amino acids.
Supplier:
Thermo Scientific Chemicals
Description:
Dinonyl phthalate (mixture of isomers) 98%
Catalog Number:
(10252-006)
Supplier:
Bioss
Description:
The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin (1). Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin (2,3). The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4). FKBP51 and FKBP52 are two highly related proteins (5,6). FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5). FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation (7). FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
Supplier:
MilliporeSigma
Description:
Stabilised with Hydroquinone Monomethyl Ether for Synthesis
Catalog Number:
(BJ40207H-2.5L)
Supplier:
Honeywell Research Chemicals
Description:
We are your supplier of high-quality lab reagents and chemicals for analytical and chemistry laboratories:
Supplier:
TCI America
Description:
CAS Number: 221682-41-3
Molecular Formula: C12H18O3 Molecular Weight: 210.27 Purity/Analysis Method: >85.0% (GC) Form: Clear Liquid Specific Gravity (20/20): 1.07
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2-Hydroxypropyl methacrylate (mixture of isomers) 97+% stabilized
Catalog Number:
(76171-728)
Supplier:
Boster Biological Technology
Description:
Rabbit IgG polyclonal antibody for Cyclophilin B detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat.
Catalog Number:
(76173-466)
Supplier:
Boster Biological Technology
Description:
Polyclonal antibody for PIN1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. PIN1 information: Molecular Weight: 18243 MW; Subcellular Localization: Nucleus . Nucleus speckle . Cytoplasm . Colocalizes with NEK6 in the nucleus (PubMed:16476580). Mainly localized in the nucleus but phosphorylation at Ser-71 by DAPK1 results in inhibition of its nuclear localization (PubMed:21497122); Tissue Specificity: The phosphorylated form at Ser-71 is expressed in normal breast tissue cells but not in breast cancer cells.
Supplier:
AMBEED, INC
Description:
Methyl-3-oxo-4-phenylbutyrate (mixture of isomers) 95%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041606-5G , MDL Number: MFCD02682433
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Dodecylbenzene sulfonic acid mixture of C10-C13 isomers
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, 2-Nonenedioic Acid (Mixture of Z and E Isomers)
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
