2-(Methylthio)pyrimidine-4,6-diol
Catalog Number:
(101819-538)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025080-500MG , MDL Number: MFCD09739208
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 049008-500MG , MDL Number: MFCD09048425
Catalog Number:
(101819-560)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025091-500MG , MDL Number: MFCD09997110
Catalog Number:
(101819-534)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025078-500MG , MDL Number: MFCD09997102
Catalog Number:
(101819-730)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025176-500MG , MDL Number: MFCD00432452
Supplier:
Matrix Scientific
Description:
MF=C18H21N3O2S MW=343.45 CAS=117977-21-6 MDL=MFCD08063845 1G
Catalog Number:
(76789-458)
Supplier:
AMBEED, INC
Description:
2-(4-((2-Aminophenyl)sulfonyl)piperazin-1-yl)ethanol, Purity: 95%, CAS Number: 1154310-76-5, Appearance: White to off-white powder or crystals, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 042520-5G , MDL Number: MFCD00140480
Supplier:
AMBEED, INC
Description:
(2-(Methoxymethoxy)-5-((trifluoromethyl)thio)phenyl)boronic acid, Purity: 97%, CAS Number: 2096331-78-9, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(101819-478)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 025050-500MG , MDL Number: MFCD00443352
Catalog Number:
(TCM1501-5G)
Supplier:
TCI America
Description:
CAS Number: 64550-71-6
MDL Number: MFCD00080808
Molecular Formula: C15H22O9S
Molecular Weight: 378.39
Purity/Analysis Method: <gt/>95.0% (HPLC)
Form: Crystal
Storage Temperature: <lt/>0°C
Catalog Number:
(101931-948)
Supplier:
Matrix Scientific
Description:
MF=C16H16N2O2S MW=300.38 MDL=MFCD00640536 500Mg
Catalog Number:
(102840-912)
Supplier:
Matrix Scientific
Description:
2-[(5-Chloropyridin-2-yl)thio]ethanol ≥97%
Catalog Number:
(TCP2521-5G)
Supplier:
TCI America
Description:
Phenyl 2,3,4,6-Tetra-O-acetyl-1-thio-A-D-mannopyranoside, Purity: >98.0%(HPLC), CAS Number: 108032-93-5, Molecular Formula: C20H24O9S, Molecular Weight: 440.46, Size: 5G
Supplier:
AMBEED, INC
Description:
(4-Aminophenyl)(4-ethylpiperazin-1-yl)methanone, Purity: 95%, CAS Number: 21312-41-4, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 250mg
Supplier:
PeproTech, Inc.
Description:
Klotho is a glycosylated protein that plays an important role in the regulation of phosphate and calcium homeostasis. Human Klotho exists in both membrane bound and secreted forms, and is predominantly expressed in the kidney convoluted tubules, and, to a lesser extent, in the brain, reproductive organs, endocrine glands, urinary bladder, skeletal muscle, placenta, and colon. The full length transmembrane form has a large extracellular domain composed of two homologous subunits termed KL1 and KL2, which contain 516 and 439 amino acid residues, respectively. The predominant circulating form, which is derived from alternative RNA splicing, contains the KL1 subunit and constitutes the N-terminal sequence of transmembrane Klotho. A third Klotho protein of about 128 kDa has been identified in the blood and cerebrospinal fluid. This circulating protein arises from the action of an as yet unidentified protease, which cleaves transmembrane Klotho just above and/or within the plasma membrane. Klotho has been shown to play a key role in the signaling cascade of fibroblast growth factor-23 (FGF-23), a bone-derived hormone that acts in the kidney to inhibit phosphate reabsorption and vitamin D biosynthesis. Klotho promotes FGF-23 signaling through binding to FGFRI (IIIc) which converts this canonical FGF receptor into a specific receptor for FGF-23. In the absence of Klotho the function of FGF-23 is literally abolished. Recombinant Human Klotho is a glycoprotein of 516 amino acid residues that migrates at an apparent molecular weight of 65-70 kDa by SDS-PAGE analysis under reducing conditions. Recombinant Human Klotho has a calculated molecular weight of 58.6 kDa.
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