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2-Chloro-5-ethoxybenzoic+acid
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2-Chloro-5-ethoxybenzoic+acid
Supplier:
AMBEED, INC
Description:
(3R,4R)-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate, Purity: 98%, CAS Number: 330681-18-0, Appearance: Powder or crystals, Storage: Keep in dark place, Inert atmosphere, 2-8C, Size: 100MG
Supplier:
Stemcell Technologies
Description:
Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2, with which it shares components of its receptor. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra, the high-affinity receptor for IL-15, as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo <i>et al.</i>). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naive CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma <i>et al.</i>).
Catalog Number:
(89358-818)
Supplier:
Genetex
Description:
The subtilisin-like Prohormone Convertase (PC) family is a group of cellular enzymes that cleave most prohormones and neuropeptide precursors. Numerous other cellular proteins, some viral proteins, and bacterial toxins that are transported by the constitutive secretory pathway are also targeted for maturation by PCs. PC family members share structural similarities, which include a heterogeneous ~10 kDa amino-terminal proregion, a highly conserved ~55 kDa subtilisin-like catalytic domain, and carboxyl-terminal domain that is heterogeneous in length and sequence. These enzymes become catalytically active following proregion cleavage within the appropriate cellular compartment. The subcellular localization of PC family members varies. Immunolocalization studies show that PC1 is found in the perinuclear region as well as the trans-Golgi network, whereas PC2 can be found in the trans-Golgi network as well as diffusely distributed in the peripheral cytoplasm.
Supplier:
Enzo Life Sciences
Description:
TRPV1 agonist
Supplier:
Adipogen
Description:
Potent platinum-based antineoplastic agent with wide spectrum anticancer activity. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Shows antitumor activity in cisplatin resistant cell lines. Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. AG-CR1-3590) and carboplatin (Prod. No. AG-CR1-3591). Apoptosis inducer. Targets other proteins and enzymes. Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2. Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake.
Catalog Number:
(10479-720)
Supplier:
Bioss
Description:
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Supplier:
Bon Opus Biosciences
Description:
Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products
Supplier:
Thermo Scientific Chemicals
Description:
D-erythro-Sphingosine is used to inhibit protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.
Supplier:
AMBEED, INC
Description:
Ethyl 3-phenylbut-2-enoate, Purity: 98%, CAS Number: 945-93-7, Appearance: Liquid, Storage: Sealed in dry, 2-8C, Size: 250MG
Supplier:
Cardinal Health
Description:
Polypropylene containers for the disposal of needles and syringes
Supplier:
TCI America
Description:
CAS Number: 6850-38-0
MDL Number: MFCD00191368 Molecular Formula: C6H13NO Molecular Weight: 115.18 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Storage Temperature: 0-10°C
Supplier:
Genscript
Description:
GenBox Gel electrophoresis system is designed to run 1 or 2 mini gels at the same time. GenBox mini tank is designed for ultimate convenience and consistent performance compared to traditional electrophoresis tanks. Discover the versatile and easy to use GenBox mini tank for your gel electrophoresis and blotting needs.
Catalog Number:
(10665-822)
Supplier:
Bioss
Description:
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Catalog Number:
(10479-718)
Supplier:
Bioss
Description:
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Catalog Number:
(10451-750)
Supplier:
Bioss
Description:
There are eight COG proteins (COG1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that COG1 is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.
Catalog Number:
(76100-514)
Supplier:
Bioss
Description:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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