4-(2-Hydroxyethyl)thiomorpholine-1,1-dioxide
Catalog Number:
(RL809-1202)
Supplier:
Rockland Immunochemical
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.
Catalog Number:
(RL810-1202)
Supplier:
Rockland Immunochemical
Description:
Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.
Catalog Number:
(RL612-6602)
Supplier:
Rockland Immunochemical
Description:
This product has been assayed against 1.0 µg of Rat IgG in a standard capture ELISA using Peroxidase Conjugated Streptavidin and ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])
Catalog Number:
(IC0855111)
Supplier:
MP Biomedicals
Description:
Product is liquid goat antiserum to human alpha-1-antitrypsin and buffer salts.
The antiserum is prepared by hyperimmunizing goats with highly purified human alpha-1-antitrypsin; antiserum is delipidated and made specific by solid-phase absorption. The resulting antiserum is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, 0.05% sodium azide, adjusted to standard titer, filtered through a 0.22 µm filter, and vialed.
Catalog Number:
(75983-072)
Supplier:
MP Biomedicals
Description:
Product is the lyophilized powder of goat antiserum to human serum and buffer salts.
The antiserum is prepared by immunizing goats with human serum; antiserum is delipidated and made specific by immunoadsorption with soluble antigens or solid-phase immunoadsorption where appropriate. The resulting antiserum is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, with 0.05% sodium azide, adjusted to standard titer, filtered through a 0.22 µm filter, vialed and lyophilized
Catalog Number:
(10247-270)
Supplier:
Bioss
Description:
Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
Catalog Number:
(10274-940)
Supplier:
Bioss
Description:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling, controlling the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
Supplier:
MP Biomedicals
Description:
Chloroquine Diphosphate salt is member of quinolone family, Chloroquine is a lysosomotropic agent (accumulate inside the acidic parts of the cell), this accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).
Catalog Number:
(10246-544)
Supplier:
Bioss
Description:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
Catalog Number:
(100504-272)
Supplier:
Electron Microscopy Sciences
Description:
CH3COONa·3H2O F.W. 136.08
A.C.S.
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Catalog Number:
(75834-592)
Supplier:
Restek
Description:
Pharmaceutical Impurities Standard, Concentration: 5,000 ug/mL each in N,N-dimethylacetamide, Compounds: Chloroethane (ethyl chloride), Chloromethane (methyl chloride), Storage: 0 deg C or colder, Volume: 1 mL/ampule
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00149863
Soluble in HCl (dilute or concentrated), alcohol, ethyl acetate, glacial acetic acid, and NaOH solution. Decomposes in excess water.
Fieser: 1,1113 15,309 16,329 17,334 18,353 19,337 20,373 21,422
Catalog Number:
(IC15801625)
Supplier:
MP Biomedicals
Description:
Ethyl violet is a cationic triarylmethane dye that is the ethyl homolog of crystal violet. It is a general histological and pathological stain.
Catalog Number:
(75932-952)
Supplier:
Rockland Immunochemical
Description:
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
Supplier:
Chem Impex International
Description:
Used as an organic phosphate donor and to buffer cell culture media.
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