Supplier:
Enzo Life Sciences
Description:
PARP inhibitor
Supplier:
Matrix Scientific
Description:
N-Propyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride
Supplier:
Spectrum Chemicals
Description:
L-Histidine Monohydrochloride, Monohydrate, also known as 2-Amino-3-(1H-imidazol-4-yl)propanoic acid, is an alpha-amino acid with an imidazole functional group.
Supplier:
AMBEED, INC
Description:
Mizoribine 98%
Supplier:
Adipogen
Description:
Selumetinib (AZD6244) is a second-generation, orally available, potent and selective ATP non-competitive inhibitor of MEK 1/2. In direct assays, AZD6244 selectively inhibits purified active MEK1 and MEK2 with an IC(50) of 14nM, and AZD6244 has reported IC(50) values of <lt/>100nm for MEK1 in ELISA assays and in bindings assays against recombinant domains of MEK2, Kd values were 53nM for AZD6244. AZD6244 demonstrated very effective anti-proliferation effects against several different cell lines with IC(50) values ranging from a low of 3nM to <lt/> 1µM depending upon the cell system used, and the compound inhibits basal and growth factor-stimulated phosphorylation of ERK1/ 2 with IC(50) concentrations <lt/> 40nM. AZD6244 has demonstrated potent dose-dependent antitumor activity against a panel of mouse xenograft models of colorectal, pancreatic, liver, skin, and lung cancer, and inhibition of tumor growth was found to correlate with the reduction of phospho-ERK1/2 levels in tumors.
Supplier:
Adipogen
Description:
Amino derivative of biotin that can be used as an intracellular label for cells, particularly neurons. It is used for neuronal tracing studies by visualizing neural architecture and for the identification of gap junction coupling. It is better soluble and non-toxic compared to other neuronal labels. It remains longer in cellsand can be fixed with formalin or glutaraldehyde. It can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
Supplier:
ALADDIN SCIENTIFIC
Description:
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.
Supplier:
AMBEED, INC
Description:
BML-277 Chk2 inhibitor 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053014-500MG , MDL Number: MFCD13562519
Supplier:
AMBEED, INC
Description:
(S)-4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052859-500MG , MDL Number: MFCD13562414
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052564-500MG , MDL Number: MFCD13562298
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052809-500MG , MDL Number: MFCD13562384
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 053196-500MG , MDL Number: MFCD13562627
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052573-500MG , MDL Number: MFCD13562307
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 052741-500MG , MDL Number: MFCD13562353
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