5-Amino-2-methyl-2H-tetrazole
Supplier:
RPI
Description:
ADP [Adenosine-5'-diphosphate, disodium salt dihydrate]
Catalog Number:
(AAJ60040-18)
Supplier:
Thermo Scientific Chemicals
Description:
Used in the cell lysis step of RNA purification. Anionic detergent
Catalog Number:
(10289-296)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(AA42773-AE)
Supplier:
Thermo Scientific Chemicals
Description:
sodium salt, 0.1% w/v Aqueous Solution,UN1170,Liquid,DANGER: FLAMMABLE, causes CNS effects, irritates skin & eyes,100ml.FLAMMABLE LIQUID,
Catalog Number:
(RC865516)
Supplier:
Ricca Chemical
Description:
1% (w/v) in 20% (v/v) Alcohol with 1% Glacial Acetic Acid. For Basal Cell Carcinoma. Container: Glass.
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Supplier:
TCI America
Description:
CAS Number: 103-32-2
MDL Number: MFCD00003018 Molecular Formula: C13H13N Molecular Weight: 183.25 Purity/Analysis Method: >98.0% (GC) Form: Crystal Boiling point (°C): 307 Melting point (°C): 37 Flash Point (°C): 113
Catalog Number:
(103508-400)
Supplier:
Acros Organics
Description:
Adenosine 5'-triphosphate, Cas number: 34369-07-8, Purity: 98%, Molecular Weight: 551.14, Molecular Formula: C10 H14 N5 Na2 O13 P3. X H2 O, Form: Powder, Solid, Color: White, Synonyms: ATP, disodium salt hydrate, Size: 10G
Catalog Number:
(100218-364)
Supplier:
Teknova
Description:
Sarkosyl (sodium lauroyl sarcosinate) is an anionic detergent that is less denaturing than SDS. Uses include solubilization of membranes and cell lysis for extraction of RNA.
Catalog Number:
(10288-048)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(10289-298)
Supplier:
Bioss
Description:
Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines, thereby repressing expression of the target gene. Dnmt3L (DNA (cytosine-5)-methyltransferase 3-like) is a 387 amino acid protein that contains one ADD-type zinc finger and is a member of the Dnmt family. Localized to the nucleus and expressed at lows levels in thymus, testis and ovary, Dnmt3L does not exhibit DNA methyltransferase activity, but is able to stimulate de novo methylation by Dnmt3 and is thought to play a key role in the establishment of genomic imprints. Additionally, Dnmt3L interacts with histone deacetylase 1 (HDAC1) and, through this interaction, mediates transcriptional repression. Multiple isoforms of Dnmt3L exist due to alternative splicing events.
Catalog Number:
(103008-354)
Supplier:
Anaspec Inc
Description:
This peptide is Histone H3 amino acid residues 1 to 21. It is trimethylated at lysine 9 with a C-terminal GG linker, followed by a biotinylated lysine. The methylation of histone H3 at lysine is an important epigenetic mark of transcriptional silencing a
Sequence:ARTKQTAR-K(Me3)-STGGKAPRKQLA-GGK(Biotin)-NH2 MW:2764.2 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(76483-188)
Supplier:
AAT BIOQUEST INC
Description:
Quin-2 binds calcium tightly and resembles calcium chelator EGTA in ability to bind calcium much more tightly than magnesium.
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Catalog Number:
(77249-150)
Supplier:
AMBEED, INC
Description:
Cyclopentyl (S)-2-((R)-2-((S)-1-hydroxy-2-(hydroxyamino)-2-oxoethyl)-4-methylpentanamido)-2-phenylacetate, Purity: 98%, CAS Number: 238750-77-1, Appearance: White to off-white solid, Storage: Keep in dark place, Sealed in dry, Store in freezer, under -20 C, Size: 1mg
Catalog Number:
(103508-398)
Supplier:
Acros Organics
Description:
Adenosine 5'-monophosphate, Cas number: 61-19-8, Purity: 99%, Molecular Weight: 347.22, Molecular Formula: C10 H14 N5 O7 P, Form: Solid, Color: Red brown, Synonyms: 5'-Adenylic acid, 5'-AMP, Size: 100G
Catalog Number:
(10167-742)
Supplier:
Genetex
Description:
Mouse Monoclonal antibody [MABI0323] to Histone H3 (tri-methyl Lys27)
Supplier:
Adipogen
Description:
ABT-737 is a small-molecule inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w, with an affinity two to three orders of magnitude more potent than previously reported compounds. Mechanistic studies reveal that ABT-737 does not directly initiate the apoptotic process, but enhances the effects of death signals, displaying synergistic cytotoxicity with chemotherapeutics and radiation. ABT-737 exhibits single-agent-mechanism-based killing of cells from lymphoma and small-cell lung carcinoma lines, as well as primary patient-derived cells, and in animal models, ABT-737 improves survival, causes regression of established tumors, and produces cures in a high percentage of the mice. ABT-737 binds to Bcl-2, Bcl-xL and Bcl-w with very high affinities (Ki <lt/>1 nM) and also shows a very high specificity over Mcl-1 and A1.
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