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Catalog Number:
(10751-216)
Supplier:
Prosci
Description:
AXIN2 Antibody: Like the related protein AXIN1, AXIN2 is thought to play an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway. In mouse, AXIN2 organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and AXIN2, which leads to the degradation of beta-catenin, which is thought to be an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Catalog Number:
(10691-152)
Supplier:
Abnova
Description:
Chicken polyclonal antibody raised against purified beta-galactosidase.
Catalog Number:
(10765-562)
Supplier:
Prosci
Description:
The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.
Catalog Number:
(102105-314)
Supplier:
Novus Biologicals
Description:
Goat Polyclonal LXR beta Antibody. Tested Applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA. Tested Reactivity: Human.
Catalog Number:
(10293-216)
Supplier:
Bioss
Description:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.
Catalog Number:
(77522-588)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, Beta) ELISA Kit
Catalog Number:
(103255-628)
Supplier:
MilliporeSigma
Description:
Anti-Beta III Tubulin Polyclonal Antibody
Catalog Number:
(77691-899)
Supplier:
LGC STANDARDS
Description:
beta-Endosulfan D4 100 µg/mL in Acetone, Dr. Ehrenstorfer, LGC Standards
Supplier:
Thermo Scientific Chemicals
Description:
N-Boc-D-aspartic acid 4-benzyl ester, 98%
Catalog Number:
(89357-418)
Supplier:
Genetex
Description:
Mouse monoclonal [100 / 1] to beta 1 + 2 Adaptin
Catalog Number:
(ABCA_AB78421-100UG)
Supplier:
ABCAM INC.
Description:
Anti-TGF beta Receptor III/TGFBR3 Mouse Monoclonal Antibody [clone: MM0057-5G9]
Catalog Number:
(76962-828)
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [HSP90AB1/3954] antibody to HSP90 beta for WB and IHC-P with samples derived from Human.
Catalog Number:
(10327-494)
Supplier:
Bioss
Description:
SMAD2 or Mothers against decapentaplegic homolog 2 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decepentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF-Beta superfamily of modulators. Like many other TGF-Beta family members SMAD2 is involved in cell signalling. SMAD2 modulates signals of activin and TGF-Beta's. It interacts with SMAD anchor for receptor activation (SARA). The binding of ligands causes the phosphorylation of the SMAD2 protein and the dissociation from SARA and the association with SMAD4. It is subsequently transferred to the nucleus where it forms complexes with other proteins and acts as a transcription factor. SMAD2 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase. Smad2 (Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2;)
Catalog Number:
(TCA1616-5G)
Supplier:
TCI America
Description:
CAS Number: 6205-69-2
MDL Number: MFCD00216968 Molecular Formula: C14H20N4O8 Molecular Weight: 372.33 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 167 Storage Temperature: <0°C
Catalog Number:
(10406-256)
Supplier:
Bioss
Description:
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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