Disodium+naphthalene-1,5-disulphonate
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Xylenol orange tetrasodium salt ACS
Supplier:
TCI America
Description:
CAS Number: 1611-35-4
MDL Number: MFCD00014580 Molecular Formula: C31H32N2O13S Molecular Weight: 716.62 Form: Crystal Color: Yellow Red
Supplier:
Adipogen
Description:
An amine-reactive blue fluorescent probe that provides a distinguishable contrast when used with longer-wavelength probes in certain multicolor fluorescence applications such as nucleic acid and protein microarrays, in situ hybridization and immunofluorescence. This carboxylic acid derivative of 7-methoxycoumarin can be used for coupling to amines, hydrazines or hydroxylamines on biomolecules of interest. Spectral data: Ex=336nm, Em=402nm (Buffer, pH9).
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Xylenol orange tetrasodium salt, water soluble, pure
Supplier:
Ricca Chemical
Description:
Xylenol orange indicator 0.2% (w/v) in alcohol
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Catalog Number:
(TCT0253-5G)
Supplier:
TCI America
Description:
CAS Number: 119-93-7
MDL Number: MFCD00014773
Molecular Formula: C14H16N2
Molecular Weight: 212.30
Purity/Analysis Method: <gt/>98.0% (GC)
Form: Crystal
Color: White
Boiling point (°C): 300
Melting point (°C): 129
Flash Point (°C): 244
Supplier:
AMBEED, INC
Description:
Xylenol orange tetrasodium salt indicator
Supplier:
Adipogen
Description:
4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as reagent for amine labelling was used successfully for derivatization and fluorescence detection of enantiomers of methamphetamin and p-hydroxymethamphetamin, in urine samples. It has also been used for 3,4-Methylendioxy-N-methylamphetamin in blood, morpholine and orther compounds. DIB-Cl as a label was used on fluorescent derivatization some hydroxyl group containing endocrine disruptors, including bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF) and 4-nonylphenol (4-NP). DIB-Cl showed superior fluorescence intensity (FI) to other commercially available reagents, excellent stability in solution and high reactivity with primary and secondary amines under mild conditions.
Supplier:
Adipogen
Description:
The BCR-ABL oncogene triggers intracellular signaling, activating multiple transduction cascades, promoting the growth, proliferation and survival of hematopoietic cells. BCR-ABL plays a role in defective DNA repair, alteration of cellular adhesion and inhibition of apoptosis. Degregulated BCR-ABL tyrosine kinase activity is the molecular marker for CML. Inhibiting BCR-ABL tyrosine kinase activity leads to the induction of apoptosis and inhibits cellular proliferation in vitro and there are various BCR-ABL isoforms with differing activity levels as well. Dasatinib (BMS-354825, Sprycel®) is a potent multi-target kinase inhibitor of BCR-ABL. Dasatiinib performs better against ABL kinase than earlier drugs such as imatinib, and Dasatinib also is effective against SRC family of kinases, and other receptor kinases such as EPHA2, PDGFR, and c-Kit. Dasatinib's inhibiting potential against Src family kinase members is greater (IC(50) 0.5nM) than its inhibitory activity against ABL (1nM).
Supplier:
TCI America
Description:
CAS Number: 135-61-5
MDL Number: MFCD00021634 Molecular Formula: C18H15NO2 Molecular Weight: 277.32 Purity/Analysis Method: >97.0% (HPLC) Form: Crystal Melting point (°C): 198
Supplier:
AMBEED, INC
Description:
1-Tosyl-1H-pyrrole, Purity: 98%, CAS Number: 17639-64-4, Appearance: Form: Crystal - Powder / Colour: White - Pale yellow or Gray, Storage: Sealed in dry, Room Temperature, Size: 1G
Catalog Number:
(75835-788)
Supplier:
Restek
Description:
The compund consists of components such as, acenaphthene (100 μg/ml), acenaphthylene (100 μg/ml), anthracene (100 μg/ml), benz(a)anthracene (10 μg/ml), benzo(a)pyrene (10 μg/ml), benzo(b)fluoranthene (10 μg/ml), benzo(ghi)perylene (10 μg/ml), benzo(k)fluoranthene (5 μg/ml), chrysene (10 μg/ml), dibenz(a,h)anthracene (10 μg/ml), fluoranthene (10 μg/ml), fluorene (100 μg/ml), indeno(1,2,3-cd)pyrene (10 μg/ml), 1-methylnaphthalene (100 μg/ml), 2-methylnaphthalene (100 μg/ml), naphthalene (100 μg/ml), phenanthrene (100 μg/ml), pyrene (10 μg/ml).
Supplier:
Honeywell Research Chemicals
Description:
Xylenol Orange tetrasodium salt, Analytical, indicator for metal titration, CAS Number: 3618-43-7, Synonym: 3, 3aE raised to 2 -Bis[N, N-bis(carboxymethyl)aminomethyl]-o-cresolsulfonephthalein tetrasodium salt, Complexometric Reagent, Size: 5G
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