5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044465-5G , MDL Number: MFCD00664561
Supplier:
Adipogen
Description:
PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model.
Catalog Number:
(101934-266)
Supplier:
Matrix Scientific
Description:
MF=C10H16Cl2N4O MW=279.17 ,250Mg
Catalog Number:
(101934-268)
Supplier:
Matrix Scientific
Description:
MF=C11H18Cl2N4O MW=293.20 ,250Mg
Catalog Number:
(76824-252)
Supplier:
AMBEED, INC
Description:
4,4'-(6-Chloropyrimidine-2,4-diyl)dimorpholine, Purity: 95%, CAS Number: 10244-24-3, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 1G
Supplier:
AMBEED, INC
Description:
2-Chloro-4-ethoxy-6-methylpyrimidine, Purity: 95%, CAS number: 37482-64-7, Appearance: Solid or liquid, Storage: Inert atmosphere, 2-8C, Size: 1G
Catalog Number:
(101933-736)
Supplier:
Matrix Scientific
Description:
MF=C12H17Cl2N5O MW=318.21 ,250Mg
Catalog Number:
(101935-292)
Supplier:
Matrix Scientific
Description:
MF=C14H24Cl2N4O MW=335.28 ,250Mg
Catalog Number:
(101935-276)
Supplier:
Matrix Scientific
Description:
MF=C14H24Cl2N4O MW=335.28 ,250Mg
Catalog Number:
(101836-092)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033646-500MG , MDL Number: MFCD11049200
Supplier:
Matrix Scientific
Description:
MF=C11H18BN3O2 MW=235.10 CAS=944401-55-2 MDL=MFCD18072554 5G
Supplier:
Adipogen
Description:
Potent protein kinase VEGFR2 inhibitor (2nm range). Binds to the pseudokinase domain of MLKL and blocks cell death by necroptosis, as well. With regards to its role in necroptosis, it is an ATP-mimetic that was shown to bind recombinant mouse MLKL pseudokinase domain, which showed inhibited TSQ-induced death of mouse dermal fibroblasts by delaying MLKL translocation to the membrane. Appears therefore to be a valuable reagent to inhibit necroptosis. It also provides an important proof-of-principle that targeting catalytically-dead pseudoenzymes represents a feasible, emerging therapeutic avenue.
Catalog Number:
(101934-254)
Supplier:
Matrix Scientific
Description:
MF=C16H18Clfn4O MW=336.80 ,250Mg
Catalog Number:
(102667-026)
Supplier:
Matrix Scientific
Description:
2-Chloro-5-fluoro-4-piperidin-1-ylpyrimidine
Catalog Number:
(77418-744)
Supplier:
APOLLO SCIENTIFIC
Description:
2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinol
Catalog Number:
(101935-786)
Supplier:
Matrix Scientific
Description:
MF=C10H17Cl2N3 MW=250.17 250Mg
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