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5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one
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5-Chloropyrazolo[1,5-a]pyrimidin-7(1H)-one
Catalog Number:
(76703-116)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Arachidonate 15-lipoxygenase B (ALOX15B) ELISA Kit
Supplier:
AMBEED, INC
Description:
Hyaluronic acid sodium salt, M.W. ~1.5-1.8 x 10E6 Da
Catalog Number:
(TCA0657-010G)
Supplier:
TCI America
Description:
CAS Number: 22577-15-7
MDL Number: MFCD00039537 Molecular Formula: C6H10O3 Molecular Weight: 130.14 Purity/Analysis Method: >95.0% (GC) Form: Clear Liquid Boiling point (°C): 192 Specific Gravity (20/20): 1.06 Storage Temperature: 0-10°C
Catalog Number:
(10435-526)
Supplier:
Bioss
Description:
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
Supplier:
AMBEED, INC
Description:
(11bS)-N,N-Bis[(1S)-1-(4-methoxyphenyl)ethyl]-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine, Purity: 95%, CAS Number: 850796-15-5, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 100MG
Supplier:
TCI America
Description:
CAS Number: 39208-15-6
MDL Number: MFCD00148920 Molecular Formula: C10H16N2O8 Molecular Weight: 397.74 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(103007-716)
Supplier:
Anaspec Inc
Description:
This is amino acids 15 to 23 fragment of the insulin beta chain recognized by islet-associated T cells. This peptide is also known as INS. It was used in diabetes studies to assay the IFN-beta and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn’t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.
Sequence: LYLVCGERG MW: 1009.2 Da % Peak area by HPLC: 95 Storage condition: -20° C
Catalog Number:
(76084-282)
Supplier:
Bioss
Description:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1.
Supplier:
AMBEED, INC
Description:
3-Bromo-2-methylbenzo[b]thiophene, Purity: 97%, CAS Number: 10243-15-9, Appearance: White to gray powder or crystals, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 250mg
Catalog Number:
(77537-490)
Supplier:
Bioss
Description:
Human Carbohydrate Antigen 15-3 (CA15-3) ELISA Kit
Supplier:
Ace Glass
Description:
The no.15 o-ring joint connections at each end
Supplier:
AMBEED, INC
Description:
7-Methoxybenzofuran-3(2H)-one 95%
Supplier:
TCI America
Description:
CAS Number: 16182-15-3
MDL Number: MFCD00007585 Molecular Formula: C9H14N2O2S Molecular Weight: 214.28 Purity/Analysis Method: >97.0% (T) Form: Crystal Melting point (°C): 114
Catalog Number:
(101826-742)
Supplier:
Matrix Scientific
Description:
1-Butyl-1H-indole-3-carbaldehyde
Supplier:
AMBEED, INC
Description:
5-Cyclohexadecen-1-one 97%
Supplier:
AMBEED, INC
Description:
2,4-Dichloro-7-fluoroquinazoline, Purity: 95%, CAS Number: 174566-15-5, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 100mg
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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