5-Phenyl-2-(trifluoromethyl)-3-furoic+acid
Supplier:
Matrix Scientific
Description:
MF=C8H4CLF3O2 MW=224.57 CAS=23228-45-7 MDL=MFCD06208178 5G
Supplier:
AMBEED, INC
Description:
5-(Trifluoromethyl)-3-pyridineboronic acid pinacol ester 98%
Supplier:
AOB CHEM USA
Description:
2-Ethoxy-4-(trifluoromethyl)benzoic acid ≥97%
Catalog Number:
(101810-640)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 020716-500MG , MDL Number: MFCD00297315
Supplier:
Matrix Scientific
Description:
(Dl)-4-(Trans-2-(Trifluoromethyl)-Cyclopropyl)Benzoic Acid, MF=C10H11NO2, MW=177.20, CAS=1404192-14-8, 100MG
Catalog Number:
(102837-436)
Supplier:
Matrix Scientific
Description:
5-Chloro-2-(trifluoromethyl)isonicotinic acid ≥97%
Catalog Number:
(101932-320)
Supplier:
Matrix Scientific
Description:
MF=C12H15Bf3No2 MW=273.07 Cas=1218790-39-6 MDL=MFCD11226774 ,500Mg
Supplier:
AMBEED, INC
Description:
8-Chloro-6-(trifluoromethyl)imidazo-[1,2-a]pyridine-2-carboxylic acid, Purity: 95%, CAS Number: 353258-35-2, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250mg
Supplier:
AMBEED, INC
Description:
2-Chloro-6-(trifluoromethyl)-4-pyridineboronic acid pinacol ester 98%
Supplier:
AOB CHEM USA
Description:
4-Ethoxy-3-(trifluoromethyl)benzoic acid ≥97%
Supplier:
AMBEED, INC
Description:
4-Nitro-2-(trifluoromethyl)phenylboronic acid 98%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 007091-5G , MDL Number: MFCD00082475
Supplier:
AMBEED, INC
Description:
4-Chloro-3,5-bis(trifluoromethyl)benzoic acid, Purity: 95%, CAS number: 773108-93-3, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Supplier:
Adipogen
Description:
Inhibitor of pan-Trk activity (IC(50) = 8 and 12nM for TrkA and TrkB). Shown to target Trk (tropomyosin receptor kinase) ATP binding cleft and an immediately adjacent hydrophobic pocket. Preferentially arrests the proliferation of Ba/F3 cells fused with Tel-TrkA, Tel-TrkB and Tel-TrkC (IC(50) = 11, 9 and 7nM, respectively) and in Ba/F3 and RIE cells expressing both TrkA and NGF (IC(50) = 42 and 17nM, respectively) over Mo7e-c-Kit and Rat-A10-PDGFR (IC(50) = 1 and 0.5µM) and Ba/F3-Tel-KDR and wt-Ba/F3 cells (IC(50) = 3.0 and 5.6µM). Displays ~100-fold greater selectivity among a panel of 59 closely related kinases and in 33 cellular kinase assays. Weakly active against relevant cytochrome P450 isozymes and hERG channel, and exhibit adequate microsomal stability, pharmacokinetic profile and efficacy in mice and rats. Suppresses tumor growth in a mouse RIE-TrkAmNGF xenograft model (50mg/kg, p.o.).
Catalog Number:
(77199-160)
Supplier:
AMBEED, INC
Description:
4-(Bromomethyl)-3-(trifluoromethyl)benzoic acid, Purity: 97%, CAS Number: 859213-39-1, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Supplier:
AMBEED, INC
Description:
2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid, Purity: 95%, CAS Number: 605680-62-4, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 C, Size: 250mg
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