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Ethyl+3,5-dichloro-4-propoxybenzoate
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Ethyl+3,5-dichloro-4-propoxybenzoate
Supplier:
Adipogen
Description:
PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nM, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nM. PF-562,271 was evaluated against multiple kinases and displays <gt/>100x selectivity against a long list of nontarget kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/mL using injections.
Supplier:
Thermo Scientific Chemicals
Description:
Vancomycin hydrochloride, 50 mg/mL in distilled water, sterile-filtered.
Supplier:
TCI America
Description:
CAS Number: 22252-43-3
MDL Number: MFCD00151456 Molecular Formula: C8H10N2O3S Molecular Weight: 214.24 Purity/Analysis Method: >98.0% (HPLC) Form: Crystal Melting point (°C): 242 Specific rotation [a]20/D: 104 deg (C=1, 1mol/L HCl)
Supplier:
TCI America
Description:
Repaglinide, Purity: >98.0%(HPLC)(T), Cas: 135062-02-1, Molecular Formula: C27H36N2O4, MW: 452.60, Synonyms: (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic Acid, Appearance: White - Very pale yellow solid crystal powder, Size: 200MG
Supplier:
BeanTown Chemical
Description:
CAS: 119-32-4; EC No: 201-924-9; MDL No: MFCD00007910; RTECS: XU8227250
UN No: UN2660; Haz Class: 6.1; Packing Group: III
Powder; Molecular Formula: C7H8N2O2 ; MW: 152.15
Melting Point: 74-77°
Supplier:
Matrix Scientific
Description:
((2R, 3S, 4R, 5R)-5-(4-Amino-2-Oxopyrimidin-1(2H)-Yl)-3, 4-Dihydroxytetrahydrofuran-2-Yl)Methyl Dihydrogen Phosphate, purity: 95+%, CAS number: 63-37-6, Molecular formula: C9H14N3O8P, Molecular weight: 323.2, Size: 100G
Catalog Number:
(10749-014)
Supplier:
Prosci
Description:
The Gap junction beta-2 protein (GJB2), also known as Connexin 26, is member of the gap junction protein family which form structures that were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. Mutations in the GJB2 gene are thought to be responsible for as much as 35-45% of congenital sensorineural hearing loss in some populations. Other mutations in this gene have also been linked to a wide array of skin diseases.
Catalog Number:
(76063-748)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000
Supplier:
TCI America
Description:
CAS Number: 5672-83-3
MDL Number: MFCD00083278 Molecular Formula: C14H17NO6 Molecular Weight: 295.29 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 71 Specific rotation [a]20/D: -25 deg (C=1, EtOH)
Supplier:
TCI America
Description:
CAS Number: 50868-73-0
MDL Number: MFCD00075455 Molecular Formula: C8H11NO Molecular Weight: 137.18 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Boiling point (°C): 116 Flash Point (°C): 113 Freezing point (°C): 28
Supplier:
Adipogen
Description:
Potent protein kinase VEGFR2 inhibitor (2nm range). Binds to the pseudokinase domain of MLKL and blocks cell death by necroptosis, as well. With regards to its role in necroptosis, it is an ATP-mimetic that was shown to bind recombinant mouse MLKL pseudokinase domain, which showed inhibited TSQ-induced death of mouse dermal fibroblasts by delaying MLKL translocation to the membrane. Appears therefore to be a valuable reagent to inhibit necroptosis. It also provides an important proof-of-principle that targeting catalytically-dead pseudoenzymes represents a feasible, emerging therapeutic avenue.
Catalog Number:
(TCF1028-1G)
Supplier:
TCI America
Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-leucine, Purity: >98.0%(HPLC)(T), CAS number: 103478-62-2, Molecular Formula: C22H25NO4, Molecular Weight: 367.45, Synonym: Fmoc-N-Me-Leu-OH, N-Fmoc-N-methyl-L-leucine, Size: 1G
Catalog Number:
(10666-812)
Supplier:
Bioss
Description:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
Catalog Number:
(10666-806)
Supplier:
Bioss
Description:
Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
Catalog Number:
(10480-548)
Supplier:
Bioss
Description:
DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Supplier:
Matrix Scientific
Description:
MF=C7H9NO MW=123.16 CAS=2835-99-6 MDL=MFCD00007871 100G
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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