7-Bromo-2,3-dihydrobenzofuran
Catalog Number:
(10748-578)
Supplier:
Prosci
Description:
IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Supplier:
Matrix Scientific
Description:
MF=C8H13BCLNO2 MW=201.46 CAS=1256355-23-3 MDL=MFCD04112542 10G
Supplier:
Thermo Scientific Chemicals
Description:
BTP-4Cl, 2,2'-((2Z,2'Z)-((12,13-bis(2-ethylhexyl)-3,9-diundecyl-12,13-dihydro-[1,2,5]thiadiazolo[3,4-e]thieno[2,3':4,5']thieno[2',3':4,5]pyrrolo[3,2-g]thieno[2,3:4,5]thieno[3,2-b]indole-2,10-diyl)(methanylylidene)(5,6-dichloro-3-oxo-2,3-dihydro-1H-diylidene), Formula: C82H86Cl4N8O2S5, Size: 250mg
Supplier:
Matrix Scientific
Description:
MF=C9H10N2O MW=162.19 Cas=69189-26-0 500Mg
Supplier:
Matrix Scientific
Description:
MF=C9H10N2O MW=162.19 Cas=1190380-38-1 1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051165-2.5G , MDL Number: MFCD08699427
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051769-2.5G , MDL Number: MFCD02937558
Catalog Number:
(102519-016)
Supplier:
Matrix Scientific
Description:
MF=C8H8INO MW=261.06 MDL=MFCD20487014 250MG
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 051266-2.5G , MDL Number: MFCD08699237
Catalog Number:
(75791-452)
Supplier:
Prosci
Description:
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
Catalog Number:
(101822-174)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 026378-500MG , MDL Number: MFCD03268044
Catalog Number:
(101850-742)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041071-250MG , MDL Number: MFCD12028517
Catalog Number:
(101918-222)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059472-250MG , MDL Number: MFCD18374139
Catalog Number:
(101827-388)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 029057-500MG , MDL Number: MFCD03419824
Catalog Number:
(101846-598)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 038987-500MG , MDL Number: MFCD09559387
Catalog Number:
(101827-382)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 029054-500MG , MDL Number: MFCD00296899
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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