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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

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7-Bromo-2,3-dihydrobenzofuran


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Catalog Number: (10748-578)

Supplier:  Prosci
Description:   IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Supplier:  Matrix Scientific
Description:   MF=C8H13BCLNO2 MW=201.46 CAS=1256355-23-3 MDL=MFCD04112542 10G
Supplier:  Thermo Scientific Chemicals
Description:   BTP-4Cl, 2,2'-((2Z,2'Z)-((12,13-bis(2-ethylhexyl)-3,9-diundecyl-12,13-dihydro-[1,2,5]thiadiazolo[3,4-e]thieno[2,3':4,5']thieno[2',3':4,5]pyrrolo[3,2-g]thieno[2,3:4,5]thieno[3,2-b]indole-2,10-diyl)(methanylylidene)(5,6-dichloro-3-oxo-2,3-dihydro-1H-diylidene), Formula: C82H86Cl4N8O2S5, Size: 250mg
Supplier:  Matrix Scientific
Description:   MF=C9H10N2O MW=162.19 Cas=69189-26-0 500Mg
Supplier:  Matrix Scientific
Description:   MF=C9H10N2O MW=162.19 Cas=1190380-38-1 1G
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 051165-2.5G , MDL Number: MFCD08699427
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 051769-2.5G , MDL Number: MFCD02937558

Supplier:  Matrix Scientific
Description:   MF=C8H8INO MW=261.06 MDL=MFCD20487014 250MG
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 051266-2.5G , MDL Number: MFCD08699237
Catalog Number: (75791-452)

Supplier:  Prosci
Description:   Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 026378-500MG , MDL Number: MFCD03268044
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 041071-250MG , MDL Number: MFCD12028517
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 059472-250MG , MDL Number: MFCD18374139
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 029057-500MG , MDL Number: MFCD03419824
Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 038987-500MG , MDL Number: MFCD09559387

Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 029054-500MG , MDL Number: MFCD00296899
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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