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Acetylenedicarboxylic+acid+monopotassium+salt
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Acetylenedicarboxylic+acid+monopotassium+salt
Catalog Number:
(76009-492)
Supplier:
Prosci
Description:
Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium. GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP. Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Crystals. For LC and molecular biology. Lot analysis on label.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Maximize the stability of your pharmaceutical formulations and get predictable pH control with reliable, proven buffering agents from Avantorâ„¢ Performance Materials.
Catalog Number:
(BDH152783K)
Catalog Number:
(BDH152803U)
Catalog Number:
(BDH152793M)
Supplier:
Honeywell Research Chemicals
Description:
Potassium dihydrogen monobasic, Purity: 99.5-100.5%, Grade: ACS, CAS: 7778-77-0, MF: KH2PO4, Molar mass: 136.09 g/mol, Synonyms: Monopotassium phosphate, Potassium dihydrogen phosphate, Container Type: poly bottle, Apps: for lab Chemical, Size: 500G
Catalog Number:
(BDH152813W)
Catalog Number:
(77442-756)
Supplier:
Teknova
Description:
Krebs-Henseleit buffer composition: 0.200% Cerelose anhydrous dextrose (Glucose), 0.014% magnesium sulfate, 0.016% monopotassium phosphate, 0.035% potassium chloride, 0.690% sodium chloride, 373 µg/ml calcium chloride and 0.210% sodium carbonate.
Supplier:
VWR International
Description:
Suitable as a titrant. Made with deionized water.
Supplier:
Honeywell Research Chemicals
Description:
Potassium dihydrogen monobasic, Purity: >/=99.0%, Grade: ACS, CAS: 7778-77-0, MF: KH2PO4, Molar mass: 136.09 g/mol, Synonyms: Monopotassium phosphate, Potassium dihydrogen phosphate, Container Type: poly bottle, Apps: for lab Chemical, Size: 6X500G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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