Supplier:
MP Biomedicals
Description:
H2O: soluble (50 mg/mL)
Supplier:
Cayman Chemical Company
Description:
ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.
Supplier:
AMBEED, INC
Description:
Adenosine 5'-monophosphate sodium salt hydrate ≥98%
Catalog Number:
(97061-106)
Supplier:
VWR
Description:
Adenosine-5"- diphosphate, disodium salt. Involved in energy and nucleic acid metabolism
Supplier:
VWR
Description:
An essential nucleotide triphosphate with a variety of roles in energy metabolism, signal transduction and nucleic acid metabolism.
Supplier:
AMBEED, INC
Description:
Adenosine-5'-diphosphoric acid (ADP) 95%
Supplier:
ALADDIN SCIENTIFIC
Description:
Adenosine-5'-diphosphoric acid (ADP) ≥95% (by HPLC), Moligand™
Supplier:
MP Biomedicals
Description:
Adenosine diphosphate, abbreviated ADP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleosideadenosine. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells.
Catalog Number:
(89151-498)
Supplier:
Enzo Life Sciences
Supplier:
New England Biolabs (NEB)
Description:
Adenosine 5´-Triphosphate (ATP) is a substrate for many ATP-dependent enzyme systems.
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Supplier:
RPI
Description:
Adenosine-5'-triphosphate disodium salt (ATP disodium salt) trihydrate
Supplier:
Thermo Fisher Scientific Chemicals Inc.
Description:
100 gm
Catalog Number:
(76688-600)
Supplier:
AMBEED, INC
Description:
Adenosine-5'-triphosphate disodium salt (ATP disodium salt) trihydrate 99%
Supplier:
AMBEED, INC
Description:
Adenosine-5'-triphosphate disodium salt (ATP disodium salt) 99%
Supplier:
MilliporeSigma
Description:
50gm. ATP, 2Na. White solid. HYGROSCOPIC. Purity:>95% by HPLC. RTECS AU7417000, CAS 987-65-5
Supplier:
MP Biomedicals
Description:
Adenosine 5'-triphosphate (ATP) disodium salt hydrate is a multifunctional nucleotide, which is essential in a variety of cellular functions.
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