Allylpalladium(II)+chloride+dimer
Catalog Number:
(10291-298)
Supplier:
Bioss
Description:
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
Supplier:
Ricca Chemical
Description:
1 ml = 0.5 mg sodium chloride. APHA for chloride.
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Supplier:
TCI America
Description:
CAS Number: 13965-03-2
MDL Number: MFCD00009593 Molecular Formula: C36H30Cl2P2Pd Molecular Weight: 701.90 Purity/Analysis Method: >98.0% (T) Form: Crystal Storage Temperature: 0-10°C
Supplier:
BeanTown Chemical
Description:
CAS: 15629-92-2; MDL No: MFCD00015318
Powder; Molecular Formula: C27H26Cl2NiP2; MW: 542.03
Melting Point: 213° (decomposes)
Supplier:
Thermo Scientific Chemicals
Description:
Very slightly soluble (with dissociation) in acetone, alcohol, chloroform, ethyl acetate, and toluene
Supplier:
AMBEED, INC
Description:
cis-Dichlorobis(triphenylphosphite)platinum(II) 98%
Supplier:
AMBEED, INC
Description:
Sodium tetrachloropalladate(II) 98%
Supplier:
BeanTown Chemical
Description:
CAS: 14220-64-5; EC No: 238-085-3; MDL No: MFCD00013123
UN No: UN3439; Haz Class: 6.1; Packing Group: III
Powder; Molecular Formula: C14H10Cl2N2Pd; MW: 383.57
Melting Point: 131°
Catalog Number:
(10252-108)
Supplier:
Bioss
Description:
CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
Catalog Number:
(10252-092)
Supplier:
Bioss
Description:
CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
Catalog Number:
(10252-112)
Supplier:
Bioss
Description:
CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
Supplier:
Thermo Scientific Chemicals
Description:
Tin(II) chloride is widely used as a reducing agent in organic synthesis, for example conversion of quinones into hydroquinones, nitroaromatics into aromatic amines, and in Stephen reduction.
Supplier:
Thermo Scientific Chemicals
Description:
Premion*, 99.95% (metals basis), Pd 14.7% min.Powder.1g,5g.
Supplier:
Thermo Scientific Chemicals
Description:
99.9% (metals basis), Pd 39% min.Crystalline,WARNING: Irritates skin and eyes,2g,10g.
Catalog Number:
(10071-866)
Supplier:
Prosci
Description:
Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
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