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Ethyl+2-chloro-1H-benzo[d]imidazole-6-carboxylate
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Ethyl+2-chloro-1H-benzo[d]imidazole-6-carboxylate
Catalog Number:
(10353-028)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(10353-020)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(10103-008)
Supplier:
Prosci
Description:
ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Lysosomal acid phosphatase is comprised of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number:
(10283-484)
Supplier:
Bioss
Description:
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
Catalog Number:
(76011-690)
Supplier:
Prosci
Description:
NUDT9 hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
Catalog Number:
(76076-324)
Supplier:
Prosci
Description:
AGPAT6 Polyclonal Antibody, Host: Rabbit, Species Reactivity: Human, Mouse, Isotype: Ig, Immunogen: KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region, Synonyms: Glycerol-3-phosphate acy
Catalog Number:
(10286-336)
Supplier:
Bioss
Description:
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
Catalog Number:
(10286-342)
Supplier:
Bioss
Description:
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
Catalog Number:
(76076-460)
Supplier:
Prosci
Description:
GPI Polyclonal Antibody, Host: Rabbit, Species Reactivity: Human, Mouse, Isotype: Ig, Immunogen: KLH conjugated synthetic peptide between 445-473 amino acids from the C-terminal region, Synonyms: Glucose-6-phosphate isomeras
Catalog Number:
(RL709-1506)
Supplier:
Rockland Immunochemical
Description:
This product has been assayed against 1.0 µg of Human IgA in a standard capture ELISA using pNPP p-nitrophenyl phosphate as a substrate for 30 minutes at room temperature.
Catalog Number:
(RL009-0633)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Biotin/Protein Ratio: 10-20 BAC molecules per Human Albumin molecule. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL Bovine Serum Albumin IgG and protease free. Lyophilized.
Catalog Number:
(10464-240)
Supplier:
Bioss
Description:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Supplier:
Bachem Americas
Description:
Sequence: 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
Synonym(s): DPPE#L-β,γ-Dipalmitoyl-α-cephalin
Catalog Number:
(10417-918)
Supplier:
Bioss
Description:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.
Catalog Number:
(76076-410)
Supplier:
Prosci
Description:
P2R3C Polyclonal Antibody, Host: Rabbit, Species Reactivity: Human, Isotype: Ig, Immunogen: KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region, Synonyms: Serine/threonine-protein phosphat
Supplier:
Biolegend
Description:
IL-21 Monoclonal Antibody, host: Mouse, Clone: 3A3-N2, Reactivity: Human, Isotype: IgG1, K, Conjugate: PerCP/Cyanine5.5, immunogen: Recombinant full length human IL-21, Formulation: Phosphate-buffered solution, Application: ICFC, Synonyms: Interleukin 21, Size: 100 tests
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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