2-(2,6-Dimethylphenylcarbamoyl)benzoic+acid
Supplier:
BeanTown Chemical
Description:
CAS: 7789-23-3; EC No: 232-151-5; MDL No: MFCD00011398; RTECS: TT0700000
UN No: UN1812; Haz Class: 6.1; Packing Group: III
Powder/Chunks; Linear Formula: KF; MW: 58.1
Melting Point: 858°; Boiling Point: 1505°
Density (g/mL): 2.48; Refractive Index: 1.363
Hygroscopic
Catalog Number:
(10329-130)
Supplier:
Bioss
Description:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].
Catalog Number:
(10407-086)
Supplier:
Bioss
Description:
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.
Catalog Number:
(10105-814)
Supplier:
Prosci
Description:
SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.
Supplier:
BeanTown Chemical
Description:
CAS: 7783-90-6; EC No: 232-033-3; MDL No: MFCD00003399; RTECS: VW3563000
UN No: UN3077; Haz Class: 9; Packing Group: III
Crystalline; Molecular Formula: AgCl; MW: 143.32
Melting Point: 455°; Boiling Point: 1550°
Density (g/mL): 5.56; Refractive Index: 2.067
Light Sensitive, Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 1336-21-6; EC No: 215-647-6; MDL No: MFCD00066650
UN No: UN2672; Haz Class: 8; Packing Group: III
Liquid, double sub-boiling quartz distillation; Linear Formula: NH4OH; MW: 35.05
Density (g/mL): 0.9
Supplier:
BeanTown Chemical
Description:
CAS: 563-63-3; EC No: 209-254-9; MDL No: MFCD00012446; RTECS: AJ4100000
UN No: UN3077; Haz Class: 9; Packing Group: III
Crystalline/Powder; Linear Formula: AgOOCCH3; MW: 166.92
Density (g/mL): 3.259
Light Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 16182-04-0; EC No: 240-318-9; MDL No: MFCD00004814
UN No: UN2924; Haz Class: 3(8); Packing Group: III
Oil; Linear Formula: SCNCOOCH2CH3; Molecular Formula: C4H5NO2S; MW: 131.15
Boiling Point: 56°/18 mmHg; Flash point: 50°C (122°F)
Density (g/mL): 1.112; Refractive Index: 1.500
Moisture Sensitive
Catalog Number:
(10357-824)
Supplier:
Bioss
Description:
Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
Catalog Number:
(76630-842)
Supplier:
Prosci
Description:
Anti-Fc gamma RIII Recombinant Antibody [Clone: 3G8]
Supplier:
BeanTown Chemical
Description:
CAS: 147-24-0; EC No: 205-687-2; MDL No: MFCD00012479
UN No: UN2811; Haz Class: 6.1; Packing Group: III
Solid; Linear Formula: (C6H5)2CHOCH2CH2N(CH3)2·HCl; Molecular Formula: C17H21NO·HCl; MW: 291.82
Light Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 38861-78-8; EC No: 254-159-8; MDL No: MFCD00027393
UN No: UN1224; Haz Class: 3; Packing Group: III
Liquid; Molecular Formula: C12H16O; MW: 176.27
Flash point: 54°C (129°F)
Density (g/mL): 0.952; Refractive Index: 1.518
Supplier:
Biotium
Description:
CD16 (Clone 3G8) is a mouse monoclonal antibody that recognizes IgG receptor CD16, also known as FC gamma receptor III. This antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.
Supplier:
BeanTown Chemical
Description:
CAS: 24596-19-8; EC No: 246-337-9; MDL No: MFCD00007826
UN No: UN2811; Haz Class: 6.1; Packing Group: III
Crystalline; Molecular Formula: C8H10BrN; MW: 200.08
Melting Point: 48-51°; Flash point: <gt/>110°C (<gt/>230°F)
Supplier:
BeanTown Chemical
Description:
CAS: 1306-23-6; EC No: 215-147-8; MDL No: MFCD00010922; RTECS: EV3150000
UN No: UN3077; Haz Class: 9; Packing Group: III
3-12mm Sintered Lump ; Molecular Formula: CdS; MW: 144.48
Melting Point: 980° (sublimes)
Density (g/mL): 4.82
Supplier:
BeanTown Chemical
Description:
CAS: 110-61-2; EC No: 203-783-9; MDL No: MFCD00001949; RTECS: WN3850000
UN No: UN3439; Haz Class: 6.1; Packing Group: III
Crystalline; Linear Formula: NCCH2CH2CN; Molecular Formula: C4H4N2; MW: 80.09
Melting Point: 50-54°; Boiling Point: 265-267°; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 0.985
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