Bis(tributyltin)+oxide
Catalog Number:
(10110-024)
Supplier:
Prosci
Description:
P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Supplier:
Spectrum Chemicals
Description:
Strontium Nitrate, Crystal, Reagent, ACS is used as an oxidizer and colorant in pyrotechnics. As an ACS grade quality reagent, its chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use. Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.
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Catalog Number:
(10103-406)
Supplier:
Prosci
Description:
APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Catalog Number:
(77245-468)
Supplier:
AMBEED, INC
Description:
(S)-1-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-phenylbut-3-en-2-amine fumarate, Purity: 97%, CAS Number: 1214741-14-6, Appearance: White to off-white solid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 250mg
Supplier:
AMBEED, INC
Description:
Iridium-(1,10-phenanthroline-KN1,KN10)bis[5-methyl-2-(4-methyl-2-pyridinyl-KN)phenyl-KC]-(OC-6-33)-hexafluorophosphate, Purity: 95%, CAS Number: 2828447-21-6, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100MG
Catalog Number:
(10408-976)
Supplier:
Bioss
Description:
Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single-stranded DNA regions of R-loop structures, and single-stranded RNA molecules. Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER. Possesses a DNA 3' phosphodiesterase activity capable of removing lesions (such as phosphoglycolate) blocking the 3' side of DNA strand breaks. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Acts as a loading factor for POLB onto non-incised AP sites in DNA and stimulates the 5'-terminal deoxyribose 5'-phosphate (dRp) excision activity of POLB. Plays a role in the protection from granzymes-mediated cellular repair leading to cell death. Also involved in the DNA cleavage step of class switch recombination (CSR). On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. Involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs).
Supplier:
Strem Chemicals Inc
Description:
BIPHEP, Phosphine
Supplier:
BeanTown Chemical
Description:
CAS: 14024-61-4; EC No: 237-859-8; MDL No: MFCD00000025
Powder; Linear Formula: Pd(C5H7O2)2; MW: 304.64
Melting Point: 200-251° (decomposes); Boiling Point: 300°
Supplier:
AMBEED, INC
Description:
(1S)-1-[Bis(1,1-dimethylethyl)phosphino]-2-[(1S)-1-(diphenylphosphino)ethyl]ferrocene, Purity: 98% 99%ee, CAS Number: 223121-01-5, Appearance: Form: powder Colour: orange, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(EM8.02712.0100)
Catalog Number:
(77621-692)
Supplier:
AMBEED, INC
Description:
11bS-N,N-Bis[(1R)-1-(1-naphthalenyl)ethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine 95%
Supplier:
AMBEED, INC
Description:
4,4'-(Hexafluoroisopropylidene)diphthalic anhydride 98%
Supplier:
Strem Chemicals Inc
Description:
P-PHOS
Supplier:
TCI America
Description:
CAS Number: 929-59-9
MDL Number: MFCD00040474 Molecular Formula: C6H16N2O2 Molecular Weight: 148.21 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Boiling point (°C): 123 Flash Point (°C): 121 Specific Gravity (20/20): 1.01
Catalog Number:
(77988-951)
Supplier:
LGC STANDARDS
Description:
1,1’-Methylene Bis[Theobromine], TRC, LGC Standards
Supplier:
AMBEED, INC
Description:
(trans,trans)-4'-Pentyl-[1,1'-bi(cyclohexan)]-4-ol, Purity: 98%, CAS Number: 82575-70-0, Appearance: White to off-white powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 10G
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