Bis(tributyltin)+oxide
Catalog Number:
(102518-958)
Supplier:
Matrix Scientific
Description:
MF=C8H3CLF6 MW=248.56 CAS=328-91-6 MDL=MFCD00632388 1G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 008806-25G , MDL Number: MFCD00042168
Catalog Number:
(77622-916)
Supplier:
AMBEED, INC
Description:
1-Methyl-1-propylpyrrolidinium bis(fluorosulfonyl)imide ≥98%
Supplier:
AMBEED, INC
Description:
Methyl 3,4-bis(benzyloxy)benzoate 97%
Catalog Number:
(10417-730)
Supplier:
Bioss
Description:
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.
Catalog Number:
(10417-742)
Supplier:
Bioss
Description:
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.
Catalog Number:
(10108-542)
Supplier:
Prosci
Description:
PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Supplier:
MP Biomedicals
Description:
BES is a zwitterionic buffer that is used in biochemistry and molecular biology research in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies.
Catalog Number:
(AAAL09516-06)
Supplier:
Thermo Scientific Chemicals
Description:
3,3-Bis(trifluoromethyl)-3-hydroxypropionic acid 3-Hydroxy-4,4,4-trifluoro-3-(trifluoromethyl)butyric acid. Grade:tech. 90, Melting Point C84-85*. Boiling Point C:NA. C5H4F6O3. 1547-36-0. CORROSIVE HA
Supplier:
Shenandoah Biotechnology
Description:
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor-alpha (TNF-α) secretion.
Supplier:
AMBEED, INC
Description:
3,4-Bis(methoxycarbonyl)phenylboronic acid 98%
Supplier:
AMBEED, INC
Description:
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile, Purity: 97%, CAS Number: 950596-58-4, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 250MG
Supplier:
AMBEED, INC
Description:
Methyl 2,4-bis(trifluoromethyl)benzoate, Purity: 98%, CAS Number: 50870-31-0, Appearance: Colorless to Almost colorless liquid, Storage: Sealed in dry, Room Temperature, Size: 5G
Catalog Number:
(TCB5142-200MG)
Supplier:
TCI America
Description:
4-Bromo-N,N-bis(9,9-dimethyl-9H-fluoren-2-yl)aniline, Purity: >97.0%(GC), CAS Number: 313050-71-4, Molecular Formula: C36H30BrN, Molecular Weight: 556.55, Size: 200MG
Supplier:
AMBEED, INC
Description:
(1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt, Purity: 98%, CAS Number: 3794-83-0, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 100g
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
![]()
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||