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CUSTOM+BIOGENIC+SYSTEMS,+INC
Catalog Number:
(76077-914)
Supplier:
Bioss
Description:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
Catalog Number:
(10396-436)
Supplier:
Bioss
Description:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
Catalog Number:
(76077-916)
Supplier:
Bioss
Description:
Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
Supplier:
Electron Microscopy Sciences
Description:
Complete kits with the following characteristics:
Supplier:
Ace Glass
Description:
A jacketed reactor base system that is designed for maximum diversity and ease of use
Supplier:
Thermo Fisher Scientific
Description:
Customer Installed Level Monitor, For Locator* 100-240V, The Ultrasonic Level Monitor safeguards irreplaceable samples with minimal liquid nitrogen evaporation and conduction, It also alerts the operator in the event of excessive liquid nitrogen loss.
Supplier:
Environmental Express
Description:
Replacement parts for the SimpleDist® Distillation Systems.
Supplier:
Hamilton
Description:
18 Gauge Dispense Tubing Custom Length 0.94 μL/mm Internal Volume
Catalog Number:
(60384-002)
Supplier:
Hamilton
Description:
Hamilton Company offers the most comprehensive selection of standard and custom syringes in the industry
Supplier:
VWR
Description:
MediaBox* Autoclavable Female adapter, capped (non-Sterile) for 8mm InteRNAl Diameter tubing (customer's own tubing required)
Catalog Number:
(76545-522)
Supplier:
BIOASSAY SYSTEMS
Description:
A reagent kit that allows our customers to develop their own cell-based ELISA. All that is required is a primary mouse antibody (Ab1).
Supplier:
Scientific Plastics
Description:
Venting systems are designed for use in acid and solvent cabinets.
Catalog Number:
(76635-466)
Supplier:
Eco Lab
Description:
The Bioquell SeQure is a fixed and compact wall-mounted bio-decontamination system. The technology utilizes Bioquell Hydrogen Peroxide Sterilant to kill microorganisms on exposed surfaces in spaces <150m3 . It offers a small footprint with fast installation and customized validated cycles performed by Ecolab validation experts on-site.
Supplier:
Sartorius
Description:
The arium pro series consists of flexible systems with a device configuration that can be custom-tailored to your applications and features an outstanding cost-benefit ratio.
Supplier:
SPECIALTY MFG CO
Description:
Easily customize strainer system to suit your application.
Supplier:
SPECIALTY MFG CO
Description:
Easily customize strainer system to suit your application.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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