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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
Supplier:
BeanTown Chemical
Description:
CAS: 10026-11-6; EC No: 233-058-2; MDL No: MFCD00011306; RTECS: ZH7175000
UN No: UN2503; Haz Class: 8; Packing Group: III
Powder; Linear Formula: ZrCl4; MW: 233.03
Melting Point: 331° (sublimes)
Density (g/mL): 2.803
Moisture Sensitive
Catalog Number:
(100243-428)
Supplier:
Southern Biotechnology
Description:
The lymphocyte Fcγ receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fcγ type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying FcγR+ cells, monoclonal antibodies to the FcγII/III receptor have been used to block Fc receptor binding of IgG, Fc-mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on FcγR for parasitic invasion. The monoclonal antibody 93 recognizes a conformational epitope formed by FcγII and FcγIII receptors.
Catalog Number:
(EM-AX0735-3)
Supplier:
BeanTown Chemical
Description:
CAS: 821-09-0; EC No: 212-473-2; MDL No: MFCD00002975
UN No: UN1987; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: H2C=CH(CH2)3OH; Molecular Formula: C5H10O; MW: 86.13
Boiling Point: 134-137°; Flash point: 48°C (118°F)
Density (g/mL): 0.834; Refractive Index: 1.429
Catalog Number:
(76084-174)
Supplier:
Bioss
Description:
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
Catalog Number:
(76629-236)
Supplier:
Prosci
Description:
Anti-C3 Recombinant Antibody [Clone: h-R3 (Nimotuzumab)]
Catalog Number:
(76630-842)
Supplier:
Prosci
Description:
Anti-Fc gamma RIII Recombinant Antibody [Clone: 3G8]
Catalog Number:
(10329-130)
Supplier:
Bioss
Description:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].
Supplier:
BeanTown Chemical
Description:
CAS: 110-85-0; EC No: 203-808-3; MDL No: MFCD00005953; RTECS: TK7800000
UN No: UN2579; Haz Class: 8; Packing Group: III
Solid; Molecular Formula: C4H10O2; MW: 86.14
Melting Point: 109-112°; Boiling Point: 145-146°; Flash point: 88°C (190°F)
Density (g/mL): 1.11
Hygroscopic , Light Sensitive
Catalog Number:
(10357-824)
Supplier:
Bioss
Description:
Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma which plays a role in meiosis.
Catalog Number:
(56620-372)
Supplier:
New Pig
Description:
Polyethylene bucket with easy-open, screw-on lid can be used to ship or temporarily store used absorbents
Supplier:
BeanTown Chemical
Description:
CAS: 124-41-4; EC No: 204-699-5; MDL No: MFCD00012179; RTECS: PC3570000
UN No: UN1289; Haz Class: 3 (8); Packing Group: III
Liquid; Linear Formula: CH3ONa; MW: 54.02
Melting Point: <lt/>6°; Boiling Point: 87°; Flash point: 11°C (52°F)
Density (g/mL): 0.945; Refractive Index: 1.370
Air Sensitive, Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 1070-83-3; EC No: 213-982-2; MDL No: MFCD00002715
UN No: UN3265; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: (CH3)3CCH2COOH; Molecular Formula: C6H11O2; MW: 116.16
Melting Point: -11°; Boiling Point: 185-190°; Flash point: 89°C (192°F)
Density (g/mL): 0.912; Refractive Index: 1.411
Catalog Number:
(76100-142)
Supplier:
Bioss
Description:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Supplier:
BeanTown Chemical
Description:
CAS: 1119-60-4; EC No: 214-283-5; MDL No: MFCD00014382
UN No: UN3265; Haz Class: 8; Packing Group: III
Liquid; Linear Formula: CH2=CH(CH2)4CO2H; Molecular Formula: C7H12O2; MW: 128.17
Melting Point: -6°; Boiling Point: 222-224°; Flash point: <gt/>110°C (<gt/>230°F)
Density (g/mL): 0.946; Refractive Index: 1.439
Catalog Number:
(75842-968)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc γ III) and CD 32 (Fc γ II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc γ I receptor.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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