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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
Catalog Number:
(10414-078)
Supplier:
Bioss
Description:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Catalog Number:
(10750-860)
Supplier:
Prosci
Description:
MYBPC1 Antibody: Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
Catalog Number:
(10485-674)
Supplier:
Bioss
Description:
FNDC8
Catalog Number:
(75843-150)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The A2F10 monoclonal antibody specifically reacts with mouse CD135, a tyrosine kinase class III receptor. CD135, also known as Flt3, Ly-72, and Flk-2, is the receptor for the FLT3 ligand (FLT3L) cytokine and is expressed on many hematopoietic progenitor cells. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. The A2F10 antibody is reported to inhibit the binding of FLT3L to CD135.
Supplier:
BeanTown Chemical
Description:
CAS: 2269-22-9; EC No: 218-871-2; MDL No: MFCD00009327
UN No: UN1992; Haz Class: 3 (6.1); Packing Group: III
Liquid; Linear Formula: Al[OCH(CH3)CH2CH3]3; Molecular Formula: C12H27AlO3; MW: 246.32
Boiling Point: 200-206°/30 mmHg; Flash point: 26°C (79°F)
Density (g/mL): 0.967
Moisture Sensitive
Catalog Number:
(75842-960)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Catalog Number:
(75842-958)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Catalog Number:
(100497-268)
Supplier:
Electron Microscopy Sciences
Description:
These suspensions are water-based and contain no additives, which may interfere with polishing or contaminate the sample. All slurries are very stable and alumina is evenly dispersed. Excellent for the finest finishes.
Catalog Number:
(75789-434)
Supplier:
Prosci
Description:
Advanced Glycosylation End Product-Specific Receptor (AGER) belongs to the immunoglobulin superfamily of cell surface molecules. It lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Besides AGEs, AGER is also able to bind other ligands which is thought to result in pro-inflammatory gene activation. It is known that AGER serve as a mediator of both acute and chronic vascular inflammation in certain conditions such as atherosclerosis and in particular as a complication of diabetes. Furthermore, it plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes.
Catalog Number:
(75791-832)
Supplier:
Prosci
Description:
Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R, as well as its paralog, EDAR, binds the ectodysplasin ligands EDA-A2 and EDA-A1, which are two alternatively spliced forms of the EDA gene. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.
Supplier:
Thermo Scientific Chemicals
Description:
Used in dry filling for thermal insulation of electrical furnaces.
Catalog Number:
(10765-518)
Supplier:
Prosci
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
Catalog Number:
(10764-658)
Supplier:
Prosci
Description:
The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
Supplier:
BeanTown Chemical
Description:
CAS: 2199-69-1; EC No: 218-606-0; MDL No: MFCD00037106
UN No: UN1591; Haz Class: 6.1; Packing Group: III
Liquid; Molecular Formula: C6D4Cl2; MW: 151.03
Boiling Point: 178-180°; Flash point: 66°C (151°F)
Density (g/mL): 1.341; Refractive Index: 1.551
Catalog Number:
(10233-172)
Supplier:
Bioss
Description:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid, in prescored ampules, 0.75ml/ampule ; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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