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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
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Carbonyldiiodo(pentamethylcyclopentadienyl)cobalt(III)
Supplier:
VWR International
Description:
VWR® Clear wide mouth bottles are manufactured from soda-lime glass that conforms to USP Type III requirements.
Supplier:
VWR International
Description:
VWR® Brand Boston Round Bottles are made from soda-lime glass that conforms to USP Type III requirements.
Catalog Number:
(JT2146-01)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
tetra-Chloroauric(III) acid trihydrate, BAKER ANALYZED® ACS
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Potassium hexacyanoferrate(III) ≥99% (by iodometry), crystals, BAKER ANALYZED® ACS
Catalog Number:
(76193-868)
Supplier:
Prosci
Description:
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (alpha and beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to a conformational change that promotes its binding to the VLH (von Hippel Lindau) protein E3 ligase complex; ubiquitination and followed by rapid proteasomal degradation. Hypoxia as well as chemical hydroxylase inhibitors (desferrioxamine, cobalt etc.) inhibit HIF-1 alpha degradation and lead to its accumulation in the cells, whereas, contrastingly, HIF-1 beta/ARNT (AhR nuclear translocator) remains stable under both conditions. Besides their critical role in hypoxic response, HIFs regulates the transcription of genes responsible for angiogenesis, erythropoiesis/iron-metabolism, glucose metabolism, cell proliferation/survival, adipogenesis, carotid body formation, B lymphocyte development and immune reactions.
Supplier:
VWR International
Description:
VWR® Amber wide mouth packer style bottles are manufactured from soda-lime glass that conforms to USP Type III requirements.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Crystals. Lot analysis on label.
Supplier:
VWR International
Description:
VWR® clear french square style bottles are manufactured from soda-lime glass that conforms to USP Type III requirements.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Crystals. Lot analysis on label.
Supplier:
VWR International
Description:
Type III jars are for collection of solid matrices or liquids dispensed from bailers or peristaltic tubing. Jars are available with solid-top or open-top caps. Solid-top caps with fluoropolymer resin liner are for use in semi-volatiles, pesticides, and PCBs; and select inorganic compounds. Open-top caps with ultrasonically bonded fluoropolymer resin/silicone septa are for use in volatile organic analysis.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Crystals. Lot analysis on label.
Supplier:
VWR International
Description:
VWR® Clear Tall Straight Sided Jars are manufactured from soda-lime glass that conforms to USP Type III requirements.
Catalog Number:
(JTM376-7)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Ferric Citrate, n-Hydrate, BAKER
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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