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DAF-FM+diacetate
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DAF-FM+diacetate
Catalog Number:
(EM8.14223.1000)
Supplier:
TCI America
Description:
CAS Number: 150-39-0
MDL Number: MFCD00004294 Molecular Formula: C10H18N2O7 Molecular Weight: 278.26 Purity/Analysis Method: >98.0% (T) Form: Crystal
Catalog Number:
(89147-634)
Supplier:
Enzo Life Sciences
Description:
Potent Raf1 kinase inhibitor (IC50=9nM). Shows ≥100-fold selectivity for Raf kinase versus CDK1, CDK2, c-Src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms.
Catalog Number:
(76082-792)
Supplier:
Bioss
Description:
FOXO1 is a transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and STK4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
Catalog Number:
(100276-108)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 1gm 466.3 Room temperature.
Supplier:
Thermo Scientific Chemicals
Description:
A diphenolic laxative that stimulates adenyl cyclase activity
Supplier:
Strem Chemicals Inc
Description:
CAS #: 5743-04-4. Size: 250g.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Cadmium acetate dihydrate 98%, pure
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Cadmium acetate dihydrate 98% for analysis
Supplier:
Thermo Scientific Chemicals
Description:
Methylbenzene. Grade:99, Melting Point ca -93*. Boiling Point C:110-111*. C7H8. 108-88-3. HIGHLY FLAMMABLE HARMFUL
Supplier:
Spectrum Chemicals
Description:
Manganese Acetate, Crystal, Reagent, also known as Manganese diacetate, is used as a catalyst, a desiccant, and as fertilizer. The Reagent grade denotes that this chemical is the highest quality commercially available and that the American Chemical Society has not officially set any specifications for this material. Spectrum Chemical manufactured Reagent grade products meet the toughest regulatory standards for quality and purity.
Supplier:
Electron Microscopy Sciences
Description:
We are now offering Lead Acetate in 25 ml bottles to avoid its classification as a hazardous chemical for shipping purposes.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Mercury(II) acetate 99+%
Supplier:
Anaspec Inc
Description:
Calcein, AM is a cell-permeant and non-fluorescent compound that is widely used for determining cell viability
Supplier:
Justrite
Description:
Essential wherever solvent cloths and wiping rags are used
Supplier:
Eagle Manufacturing
Description:
Designed for use as an intermediate station for liquid wastes.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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