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Dai+Ki+Sciences+Co.+(USD)+Ltd
Supplier:
CHI Scientific
Description:
OptiTDSâ„¢ is a proprietary Tissue Dissociation system which enzymatically digests extracellular connective fibers without harming the cells themselves
Catalog Number:
(82022-768)
Supplier:
G-Biosciences
Description:
G-Biosciences' Botanical Garden Blot is prepared using total protein extracted from a variety of 5-10 day old, whole plant tissues.
Catalog Number:
(10340-134)
Supplier:
Bioss
Description:
Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Catalog Number:
(76486-062)
Supplier:
Janitorial Supplies
Description:
Designed especially for people who work on their feet all day on hard or uneven surfaces and experience discomfort and fatigue in their feet and legs.
Catalog Number:
(76461-802)
Supplier:
Janitorial Supplies
Description:
Use this wall calendar as a writing surface to jot down notes, ideas, appointments, reminders, and more. Dated planning pages range 12 months from January to December.
Supplier:
Argos Technologies
Description:
The Cole-Parmer® PolarSafe® dewar together with a Traceable® data logger is the perfect combination to safely store your critical samples while maintaining sample integrity.
Supplier:
AmTab Manufacturing Corporation
Description:
Heavy-duty stage ramp carts are used every day in conjunction with our stage and stage ramp units. High-quality state-of-the-art guard rail carts are safe, durable, easy to operate, and a great long-term value. Carts are perfect for heavy-use and heavy-turn settings providing years of trusted service.
Supplier:
Adipogen
Description:
GSK2126458 is an orally available selective inhibitor of the class I phosphoinositide 3-kinase (PI3K) enzymesand MTOR1/2 complexes. GSK2126458 can inhibit PI3K-alpha (p85alpha/p110alpha) with IC(50) of 0.04nM. GSK2126458 has Ki values in the picomolar range for each of the class I PI3K isoforms and MTOR1/2 complexes. GSK2126458 has potent in vitro and in vivo growth-inhibitory effects on cancer cells. In comparison with other clinical PI3K inhibitors, GSK2126458 is around 100-fold more potent than BEZ235 (6nM). GSK2126458 also a low picomolar inhibitor of the common activating mutants of p110R ( E542K, E545K, and H1047R ) with Ki of 0.008nM, 0.008nM and 0.009nM in human cancer. In mechanistic cellular assays, GSK2126458 caused a significant reduction in the levels of pAKT-S473 with remarkable potency. Consistent with its activity against both PI3K R and mTOR, GSK2126458 also inhibits phosphorylation of AKT-T308 and p70S6K at low nanomolar concentrations. GSK2126458 induces a G1 cell cycle arrest and inhibits cell proliferation in a large panel of cell lines, including T47D and BT474 breast cancer lines.
Catalog Number:
(77439-842)
Supplier:
Bioss
Description:
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
Catalog Number:
(76744-280)
Supplier:
ANTIBODIES.COM LLC
Description:
Human Myosin Light Chain Kinase/MLCK ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Myosin Light Chain Kinase/MLCK in serum, plasma, tissue homogenates, and other biological fluids.
Supplier:
GE Healthcare - HyClone
Description:
HyCloneâ„¢ Cosmic calf serum is fortified with iron and naturally derived components for increased performance with a broad spectrum of cell type. Contains high quality iron-supplemented bovine calf serum with added growth promoting factors.
Supplier:
AmTab Manufacturing Corporation
Description:
These computer/technology tables, are used every day throughout the world in a variety of media and tech environments. High-quality state-of-the-art tables are safe, durable, easy to operate, and perfect for heavy-use and heavy-turn settings providing years of trusted service.
Supplier:
GFS Chemicals
Description:
Meets EPA linear calibration recommendations
Catalog Number:
(470146-202)
Supplier:
LaMotte
Description:
Economical Water Testing Solution
Supplier:
AmTab Manufacturing Corporation
Description:
Mobile folding tables are used every day throughout the world in multi-purpose environments. High-quality state-of-the-art tables are safe, durable, easy to operate, and a great long-term value.
Catalog Number:
(10790-764)
Supplier:
Hach
Description:
One unit each of the reagents is sufficient for 30 days of operation
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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