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Deuterium+oxide
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Deuterium+oxide
Supplier:
Shenandoah Biotechnology
Description:
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
Supplier:
BeanTown Chemical
Description:
CAS: 7732-18-5; EC No: 231-791-2; MDL No: MFCD00011332
Liquid; Molecular Formula: H2O ; MW: 18.02
Melting Point: 0°; Boiling Point: 100°
Density (g/mL): 1.000; Refractive Index: 1.333
Catalog Number:
(10232-306)
Supplier:
Bioss
Description:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Catalog Number:
(10330-966)
Supplier:
Bioss
Description:
Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
Supplier:
MilliporeSigma
Description:
A tripeptide that serves as a component of the [gamma]-glutamyl amino acid transport system. An endogenous antioxidant that provides protection against auto-oxidation.
Supplier:
Spectrum Chemicals
Description:
Cab-O-Sil(R) M-5, Scintillation Grade, also known as fumed silica and pyrogenic silica and is made up of microscopic drops of amorphous silica bonded into branched secondary particles. Scintillation grade products from Spectrum are of a suitable purity for use in fluorescence - luminescence spectroscopy applications
Catalog Number:
(10320-934)
Supplier:
Bioss
Description:
Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Supplier:
GLOBAL LIFE SCIENCES SOLUTIONS
Description:
Water for Injection (WFI) USP grade is a terminally distilled, sterile, non-pyrogenic preparation which contains no bacteriostat, antimicrobial agent or added buffer. It complies with the USP monograph for water for injection packaged in bulk for commercial use..
Catalog Number:
(10238-308)
Supplier:
Bioss
Description:
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Zirconyl nitrate hydrate 99.5% contains up to 4% Hf
Supplier:
AAT BIOQUEST INC
Description:
Luciferin is the most popular and versatile bioluminescent substrate.
Catalog Number:
(10387-002)
Supplier:
Bioss
Description:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Catalog Number:
(10417-746)
Supplier:
Bioss
Description:
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.
Catalog Number:
(101094-416)
Supplier:
Thermo Scientific Chemicals
Description:
With bromide ion, catalyzes the liquid-phase auto-oxidation of cresols.
Catalog Number:
(100204-756)
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7803-55-6. Size: 5g.
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