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Deuterium+oxide


8,742  results were found

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Supplier:  Bioss
Description:   Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Supplier:  MP Biomedicals
Description:   Thioglycolic acid protects tryptophan in amino acid analysis,and also mediates formation of ATP from ADP. It lowers the oxidation-reduction potential and neutralises mercurial preservatives. An inhibitor of fatty acid oxidation. An agent that prevents the metabolism of fatty acids and stimulates feeding. The sodium salt form is typically used in production of bacteriological culture media. The free acid is used as a reagent for the sensitive detection of iron (a blue color appears in the presence of ferric iron, and when an alkali hydroxide is added to a solution containing ferrous salts and thioglycolic acid, a yellow precipitate forms), molybdenum, silver and tin; used for the extraction and spectrophotometric determination of various transition metals such as lead, tungsten, molybdenum and titanium.
MSDS SDS

Supplier:  Bioss
Description:   Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Catalog Number: (76012-066)

Supplier:  Prosci
Description:   SUMO4 is a member of the SUMO gene family. This family of small ubiquitin-related modifiers covalently modify target lysines in proteins and control the target proteins' subcellular localization, stability, or activity. Upon oxidative stress, SUMO4 conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. This protein may also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to SUMO4 substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. In contrast to SUMO1, SUMO2 and SUMO3, SUMO4 seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90. This may impair processing to mature form and conjugation to substrates. SUMO4 is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. The M55V substitution has been associated with type I diabetes.
Supplier:  Rockland Immunochemical
Description:   LOXL1 is a member of the lysyl oxidase gene family which is essential to the biogenesis of connective tissue. LOXL1 encodes an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. LOXL1 is responsible for catalyzing the oxidative deamination of lysine residues of tropoelastin and this deamination causes spontaneous cross-linking and formation of elastin polymer fibers (1). LOXL1 serves both as a crosslinking enzyme and an element of the scaffold to ensure spatially defined deposition of elastin (2). LOXL1 Protein is ideal for investigators involved in Signaling Proteins, Lysyl Oxidase Proteins, Cancer, and Metabolic Disorder research.
Supplier:  BeanTown Chemical
Description:   CAS: 25322-68-3; MDL No: MFCD01779605; RTECS: TQ4025000 Powder; Linear Formula: H(OCH2CH2)nOH; MW ≈1,000 Melting Point: 35-40°; Flash point: 229°C (444°F) Density (g/mL): 1.2
MSDS SDS
Supplier:  Spectrum Chemicals
Description:   Magnesium Chloride, Hexahydrate, Crystal, USP, EP, BP is used as a nutritional supplement. All Spectrum Chemical USP, EP, BP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Small Business Enterprise
Supplier:  Bioss
Description:   The amino acid Citrulline is required to detoxify the liver from ammonia, which is a waste product of the body from oxidation. Citrulline promotes energy and assists with the immune system. This unusual amino acid is formed in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. It is then combined with aspartic acid to form arginosuccinic acid, which later is metabolized into the amino acid arginine.

Supplier:  Bioss
Description:   The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
Supplier:  Spectrum Chemicals
Description:   Sodium Chlorite, Anhydrous, Flakes is a chemical compound often used in the manufacture of paper. Used to generate chlorine dioxide for the bleaching and striping of textiles it is also frequently used as a oxidation reagent in organic synthesis.
MSDS SDS
Small Business Enterprise
Catalog Number: (100503-692)

Supplier:  Electron Microscopy Sciences
Description:   Can be used for staining synapses (Pfenninger, K., Sandri, C., Albert, K. and Eugster, C.H., 1969). Contribution of the problem of structural organization of the presynaptic area (Brain Res., 12:10).
Minority or Woman-Owned Business Enterprise

Supplier:  Bioss
Description:   Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Supplier:  Bioss
Description:   ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Catalog Number: (89358-018)

Supplier:  Genetex
Description:   ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Supplier:  Electron Microscopy Sciences
Description:   These gold coated tweezers are finely crafted, high precision tweezers made from anti-acidic, non-magnetic stainless steel, plated with 2 microns of pure 24-carat gold

Supplier:  Bioss
Description:   SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.
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