Dibenzyl+phosphate
Catalog Number:
(76078-030)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(76422-446)
Supplier:
Biolegend
Description:
CD127, Monoclonal Antibody, Clone: S18006K, Host: Rat, Species Reactivity: Mouse, Isotype: IgG, Immunogen: mouse IL7R-transfectants, Other Names: IL-7 receptor A chain, IL-7RA, Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide, Size: 500 uG
Catalog Number:
(77438-252)
Supplier:
Bioss
Description:
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.
Catalog Number:
(10068-814)
Supplier:
Prosci
Description:
Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3, 4, 5-trisphosphate, phosphatidylinositol 3, 4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3, 4, 5)P3 > PtdIns(3, 4)P2 > PtdIns3P > Ins(1, 3, 4, 5)P4. The lipid phosphatase activity is critical for its tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation. Dephosphorylates tyrosine-phosphorylated focal adhesion kinase and inhibits cell migration and integrin-mediated cell spreading and focal adhesion formation. May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
Catalog Number:
(RL001-0033)
Supplier:
Rockland Immunochemical
Description:
1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 4 moles TRITC per mole of Bovine Albumin. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL polyethylene glycol. For research. Lyophilized.
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Catalog Number:
(10108-560)
Supplier:
Prosci
Description:
AK3L1 is a member of the adenylate kinase family of enzymes. The protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides.This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
Catalog Number:
(10298-822)
Supplier:
Bioss
Description:
This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.[provided by RefSeq, Feb 2010].
Catalog Number:
(EM-EX0993-20)
Supplier:
MilliporeSigma
Description:
Extran® MA 01 is a universal cleaner for the removal of heavy contamination. In wiping tables, tiles, floors. In soaking for the automated cleaning of laboratory equipment.
Catalog Number:
(76422-346)
Supplier:
Biolegend
Description:
CD28 Monoclonal Antibody, host: Mouse, Clone: CD28.2V-CD28.05, Reactivity: Human, Isotype: IgG1, K, Conjugate: PE, Formulation: Phosphate-buffered solution, pH 7.2, Storage: should be stored undiluted between 2deg C and 8deg C and, Application: FC, Synonyms: T44, Tp44, Size: 500 uL
Catalog Number:
(76422-348)
Supplier:
Biolegend
Description:
CD28 Monoclonal Antibody, host: Mouse, Clone: CD28.2V-CD28.05, Reactivity: Human, Isotype: IgG1, K, Conjugate: APC, Formulation: Phosphate-buffered solution, pH 7.2, Storage: should be stored undiluted between 2deg C and 8deg C and, Application: FC, Synonyms: T44, Tp44, Size: 500 uL
Catalog Number:
(76083-468)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(10353-006)
Supplier:
Bioss
Description:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Catalog Number:
(76422-608)
Supplier:
Biolegend
Description:
TIGIT, Monoclonal Antibody, Clone: 1G9, Host: Mouse, Species Reactivity: Mouse, Isotype: IgG1, K, Conjugate: TotalSeq-C0848, Other Names: VSIG9, Formulation: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide and 1 mM EDTA, Application: PG, Size: 10 uG
Catalog Number:
(76422-218)
Supplier:
Biolegend
Description:
CD66b Monoclonal Antibody, host: Mouse, Clone: G10F5VI MA81, Reactivity: Human, Isotype: IgM, K, Conjugate: FITC, Formulation: Phosphate-buffered solution, pH 7.2, Storage: should be stored undiluted between 2deg C and 8deg C and, Application: FC, Synonyms: CD67, CGM6, Size: 500 uL
Catalog Number:
(76422-344)
Supplier:
Biolegend
Description:
CD7 Monoclonal Antibody, host: Mouse, Clone: CD7-6B7, Species Reactivity: Human, Isotype: IgG2a, K, Conjugate: PE, Formulation: Phosphate-buffered solution, pH 7.2, Storage: should be stored undiluted between 2deg C and 8deg C and, Application: FC, Synonyms: gp40, Size: 500 uL
Supplier:
Biolegend
Description:
CD8a Monoclonal Antibody, Clone: 53-6.7, Host: Rat, Species reactivity: Mouse, Isotype: IgG2a,K, Conjugate: Spark NIR685, Immunogen: Mouse thymus or spleen, Formulation: Phosphate-buffered solution, pH7.2, Synonyms: T8, Lyt2, Storage: between 2 deg C and 8 deg C, Application: FC, Size: 100ug
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