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Dibutyryl-cGMP
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Dibutyryl-cGMP
Catalog Number:
(10393-740)
Supplier:
Bioss
Description:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Catalog Number:
(89297-842)
Supplier:
Genetex
Description:
Goat polyclonal antibody to PDE5A
Supplier:
GLOBAL LIFE SCIENCES SOLUTIONS
Description:
Cytiva's Purified Water, USP can be used as an excipient in the production of non-parenteral preparations such as cleaning of certain equipment and non-parenteral product-contact components.
Supplier:
Spectrum Chemicals
Description:
Calcium Chloride, Anhydrous, Pellets, FCC is used as a sequestrant and firming agent in food products. It is considered as generally recognized as safe (GRAS) by the U.S. Food and Drug Administration. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Spectrum Chemicals
Description:
All-rac-a-Tocopheryl Acetate, FCC is the synthetic form of Vitamin E. Alpha-tocopheryl acetate is more resistant to oxidation during storage than unesterified tocopherols. The bioavailability of alpha-tocopherol from alpha-tocopheryl acetate is roughly equivalent to that of free alpha-tocopherol. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Spectrum Chemicals
Description:
Alcohol, 190 Proof, USP is approximately 95% Ethanol and 5% water. This product, 190 proof USP grade alcohol, is used as an antiseptic to disinfect skin prior to injections and as a solvent. All Spectrum Chemical USP products, including all USP alcohol products, are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Catalog Number:
(10300-334)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble forms, known as GCS or sGC, act as receptors for nitric oxide. The membrane-bound receptor forms, known as GC, are peptide hormone receptors. GCS, a cGMP-synthesizing enzyme, is the major receptor for the neurotransmitter nitric oxide (NO). It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme containing heterodimer, consisting of one alpha subunit, designated GCS-alpha-1, and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide, which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both the alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity.
Catalog Number:
(76014-996)
Supplier:
Spectrum Chemicals
Description:
Ursodiol, USP is a bile acid used to prevent and dissolve certain types of gallstones. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Spectrum Chemicals
Description:
BISMUTH CITRATE, POWDER, USP is used as an internal deodorant and treats malodor by deodorizing flatulence and stool odors. It is usually given to people who suffer from fecal incontinence, IBS or who have has ostomy surgery or bariatric surgery. Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Storage temperature - LIGHT SENSITIVE: Keep tightly closed in light-resistant containers.
Supplier:
Spectrum Chemicals
Description:
Ascorbyl Palmitate, NF is often used to promote flow of tableting powders and to prevent their sticking in tablet presses.Â
Supplier:
Spectrum Chemicals
Description:
Hypromellose, Substitution Type 2208, 100,000 mPa.s, USP.Â
Supplier:
Spectrum Chemicals
Description:
Sucrose Octaacetate, NF is FDA approved for use as an food additive, Its bitter taste makes it ideal as a bitterant and aversive agent. It is used in pharmaceutical product containing ethanol to denature the ethanol and is industrially used as an ingredient in herbicides in an inert form. Spectrum Chemical NF products, including all NF Sucrose products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Storage temperature - HYGROSCOPIC: Keep tightly closed.
Supplier:
Spectrum Chemicals
Description:
Magnesium Oxide, Heavy Powder, USP has many uses, but from a pharmaceutical perspective it is used primarily as a mineral supplement and a tablet and capsule diluent.Â
Catalog Number:
(95032-950)
Supplier:
Spectrum Chemicals
Description:
Diphenhydramine Hydrochloride, USP is an antihistamine that includes sedative attributes to treat allergies. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Supplier:
Spectrum Chemicals
Description:
Carboxymethylcellulose Sodium, Low Viscosity, Viscosity of 2 Percent Aqueous Solution @ 25 DEG C: 37.5 cP, USP is often used as a thickener and stabilizer. The USP grade indicates it is a grade suitable for personal care, cosmetic and pharmaceutical applications and were manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Supplier:
Spectrum Chemicals
Description:
Ethyl Cellulose, FCC, a derivative of cellulose, is often used as an emulsifier food additive. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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