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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Supplier:
AMBEED, INC
Description:
4,6-Dichloro-5-iodopyrimidine 98%
Supplier:
Thermo Scientific Chemicals
Description:
As, B, P, S, Se, Si, Te at concentration 100µg/ml in 5% HCL with a trace of HF
Catalog Number:
(TS46243-2500)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Ziprasidone hydrochloride monohydrate
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Mycophenolate Mofetil EP Impurity A HCl (O-Desmethyl Impurity HCl)
Catalog Number:
(76262-930)
Supplier:
Rockland Immunochemical
Description:
AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer.  AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation.
Catalog Number:
(77990-677)
Supplier:
LGC STANDARDS
Description:
p-NH2-Bn-NOTA HCl Salt, TRC, LGC Standards
Catalog Number:
(45603-330)
Supplier:
PERKINELMER U.S. LLC
Description:
Single Element Luminaâ„¢ hollow cathode lamp (HCL) for the detection of elemental Praseodymium (Pr). Series N30501XX Luminaâ„¢ 2" (50 mm) diameter single-element lamps are designed to be used with our PinAAcleâ„¢ and AAnalystâ„¢ atomic absorption spectrometer series of instruments.
Catalog Number:
(45603-372)
Supplier:
PERKINELMER U.S. LLC
Description:
Single Element Luminaâ„¢ hollow cathode lamp (HCL) for the detection of elemental Ytterbium (Yb). Series N30501XX Luminaâ„¢ 2" (50 mm) diameter single-element lamps are designed to be used with our PinAAcleâ„¢ and AAnalystâ„¢ Atomic Absorption spectrometer series of instruments.
Catalog Number:
(10446-344)
Supplier:
Bioss
Description:
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
Catalog Number:
(10351-028)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Catalog Number:
(10351-030)
Supplier:
Bioss
Description:
Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.
Supplier:
AMBEED, INC
Description:
Nα-Benzyloxycarbonyl-L-lysine thiobenzyl ester hydrochloride ≥97%
Supplier:
HCL Label
Description:
HCL's liquid biowaste label is made of a durable adhesive vinyl.
Supplier:
AOB CHEM USA
Description:
2,6-Dichloro-3-fluoro-4-iodopyridine ≥97%
Supplier:
Matrix Scientific
Description:
MF=C5HCL2N3 MW=173.99 CAS=3177-24-0 MDL=MFCD09746248 1G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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