Text Search >
Diethyl+malonate
Print…
You Searched For:
1,833 results were found
Diethyl+malonate
Supplier:
Adipogen
Description:
The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590 nm) in healthy cells. After cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529 nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio.
Supplier:
AMBEED, INC
Description:
(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate, Purity: 99+%, CAS Number: 1872382-47-2, Appearance: White to off white powder or crystals, Size: 25mg
Supplier:
Rockland Immunochemical
Description:
Molecular Biology Grade Ultrapure water is suitable for molecular immunology, molecular biology and nucleic acid methodologies, when applicable. It is commonly used in laboratory to prepare buffers in biochemistry and molecular biology laboratories and also cell culture media for cell biology studies.
Supplier:
MP Biomedicals
Description:
Chloroquine Diphosphate salt is member of quinolone family, Chloroquine is a lysosomotropic agent (accumulate inside the acidic parts of the cell), this accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).
Catalog Number:
(BT132745-5G)
Supplier:
BeanTown Chemical
Description:
CAS: 111-74-0; EC No: 203-902-4; MDL No: MFCD00009033
UN No: UN2685; Haz Class: 8 (3); Packing Group: II
Liquid; Linear Formula: CH3CH2NHCH2CH2NHCH2CH3; Molecular Formula: C6H16N2; MW: 116.21
Boiling Point: 152-154°; Flash point: 33°C (91°F)
Density (g/mL): 0.811; Refractive Index: 1.433
Catalog Number:
(TCD1703-25ML)
Supplier:
TCI America
Description:
CAS Number: 3616-56-6
MDL Number: MFCD00009232 Molecular Formula: C8H19NO2 Molecular Weight: 161.25 Purity/Analysis Method: >97.0% (GC,T) Form: Clear Liquid Boiling point (°C): 60 Flash Point (°C): 45 Specific Gravity (20/20): 0.87
Supplier:
MilliporeSigma
Description:
For molecular biology. Prepared with diethyl pyrocarbonate for RNA applications. DNase-, RNase-, and protease-free.
Supplier:
RPI
Description:
Irreversible serine protease inhibitor of chymotrypsin, kallikrein, papain, subtilisin, thrombin and trypsin. Working conentration is 0.1 to 1.0 mM.
Catalog Number:
(100504-314)
Supplier:
Electron Microscopy Sciences
Description:
An organo-silicon compound tetramethylsilane (TMS) is used as an internal standard for nuclear magnetic resonance (NMR).
Catalog Number:
(75835-544)
Supplier:
Restek
Description:
The mix consists of acetonitrile, acrylonitrile, allyl chloride , benzene, bromobenzene, bromochloromethane, bromodichloromethane, bromoform, n-butylbenzene, sec-butylbenzene, tert-butylbenzene, carbon disulfide, carbon tetrachloride, chlorobenzene, 2-chloroethanol, chloroform, chloroprene , 2-chlorotoluene, 4-chlorotoluene, dibromochloromethane, 1,2-dibromo-3-chloropropane , 1,2-dibromoethane , dibromomethane, 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,4-dichlorobenzene, cis-1,4-dichloro-2-butene, trans-1,4-dichloro-2-butene, 1,1-dichloroethane, 1,2-dichloroethane, 1,1-dichloroethene, cis-1,2-dichloroethene, trans-1,2-dichloroethene, 1,2-dichloropropane, 1,3-dichloropropane, 2,2-dichloropropane, 1,1-dichloropropene, cis-1,3-dichloropropene, trans-1,3-dichloropropene, diethyl ether , 1,4-dioxane, ethylbenzene, ethyl methacrylate, hexachloro-1,3-butadiene, iodomethane , isobutyl alcohol , isopropylbenzene , 4-isopropyl toluene , methacrylonitrile, methyl acrylate, methyl methacrylate, methylene chloride , naphthalene, nitrobenzene, 2-nitropropane, propionitrile, n-propylbenzene, styrene, 1,1,1,2-tetrachloroethane, 1,1,2,2-tetrachloroethane, tetrachloroethene, tetrahydrofuran, toluene, 1,2,3-trichlorobenzene, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloroethene, 1,2,3-trichloropropane, 1,1,2-trichlorotrifluororethane , 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene, m-xylene, o-xylene, p-xylene.
Catalog Number:
(AA87324-AP)
Supplier:
Thermo Scientific Chemicals
Description:
Methylmagnesium bromide, 3M in ether, Cas Number: 75-16-1, Molecular Formula: CH3BrMg, Color: Light brown, Form: Liquid, Size: 500ML
Supplier:
Thermo Scientific Chemicals
Description:
3M in ether, packaged under Argon in resealable ChemSeal– bottles,UN3207,Liquid,DANGER: FLAMMABLE, burns skin & eyes, air & water sensitive,1mole,0.5mole,DANGEROUS WHEN WET,FLAMMABLE LIQUID
Supplier:
MP Biomedicals
Description:
Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle.
Urea is a mild agent usually used in the solubilization and denaturation of proteins. It is also useful for renaturing proteins from samples already denatured with 6 M guanidine hydrochloride such as inclusion bodies; and in the extraction of the mitochondrial complex. It is commonly used to solubilize and denature proteins for denaturing isoelectric focusing and two-dimensional electrophoresis and in acetic acid-urea PAGE gels. Urea is used in cell or tissue culture media to increase the osmolality. Urea has also been used as fertilizer because of the easy availability of nitrogen; in animal feeds; it is reacted with aldehydes to make resins and plastics; condensed with malonic ester to form barbituric acid; used in the paper industry to soften cellulose; used as a diuretic; enhances the action of sulfonamides; an antiseptic. Urea in solution is in equilibrium with ammonium cyanate. The form that reacts with protein amino groups is isocyanic acid. Urea in the presence of heat and protein leads to carbamylation of the proteins. Carbamylation by isocyanic acid interferes with protein characterization because isocyanic acid reacts with the amino terminus of proteins, preventing N-terminal sequencing. Isocyanic acid also reacts with side chains of lysine and arginine residues resulting in a protein that is unsuitable for many enzymatic digests. In addition, carbamylation often leads to confusing results from peptides having unexpected retention times and masses. When performing enzymatic protein digests it is important to remove urea first. Even though some enzymes will tolerate small amounts of urea, the elevated temperature used for most reactions will lead to carbamylation during the course of the digest. The urea can be removed prior to digestion by fast reversed phase chromatography, spin columns, or dialysis. Dissolve urea in deionized water to the desired concentration.For every 10 ml of solution, add 1 g of Amberlite® IRA-910.Stir for one hour at room temperature
Catalog Number:
(IC10223201)
Supplier:
MP Biomedicals
Description:
Maleic acid (MA) is a dicarboxylic acid that undergoes esterification with ethanol in the presence of cation-exchange resin catalysts to form diethyl maleate. Its crystalline structure has been analyzed. Reaction kinetics and mechanism of the isomerization of maleic acid to fumaric acid in the presence of ceric and bromide ions has been investigated. The reaction mechanism and reactivity ratios for the radical copolymerization of maleic acid with styrene have been determined.
Catalog Number:
(10264-696)
Supplier:
Bioss
Description:
GSS (Glutathione synthetase) is a 474 amino acid protein encoded by the gene located at human chromosome 20q11.2. GSS consists of three loops projecting from an antiparallel ∫-sheet, a parallel ∫-sheet and a lid of anti-parallel sheets, which provide access to the ATP-binding site. Although Southern blot and gene analysis suggest that GSS may be the only member of a unique family, the crystal structure indicates that GSS belongs to the ATP-GRASP superfamily. GSS is expressed in hemocytes and nucleated cells, including the brain. GSS occurs as a homodimer. There are two steps in the production of Glutathione, begining with GSS (Glutathione synthetase) is a 474 amino acid protein encoded by the gene located at human chromosome 20q11.2. GSS consists of three loops projecting from an antiparallel ∫-sheet, a parallel ∫-sheet and a lid of anti-parallel sheets, which provide access to the ATP-binding site. Although Southern blot and gene analysis suggest that GSS may be the only member of a unique family, the crystal structure indicates that GSS belongs to the ATP-GRASP superfamily. GSS is expressed in hemocytes and nucleated cells, including the brain. GSS occurs as a homodimer. There are two steps in the production of Glutathione, begining with ©-GCS and ending with GSS. In an ATP-dependent reaction, GSS produces Glutathione from ©-glutamylcysteine and glycine precursors. Partial hepatectomy, diethyl maleate, buthionine sulfoximine, tert-butylhaydroquinone and thioacetamide increase the ex-pression of GSS, which causes an increase in Glutathione levels. An inherited autosomal recessive disorder, 5-oxoprolinuria (pyroglutamic aciduria), is caused by GSS deficiencies, which leads to central nervous system damage, hemolytic anemia, metabolic acidosis and urinary excretion of 5-oxoproline. A missense mutation in the gene encoding GSS leads to a GSS deficiency restricted to erythrocytes, which causes only hemolytic anemia.-GCS and ending with GSS.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
|
|||||||||
List View
