Ditetradecyl-3,3\'-thiodipropionate
Catalog Number:
(77625-686)
Supplier:
AMBEED, INC
Description:
(5S)-6,6'-Bis(di-p-tolylphosphaneyl)-2,2',3,3'-tetrahydro-5,5'-bibenzo[b][1,4]dioxine ≥97%
Supplier:
AMBEED, INC
Description:
1-(6-(4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl)-2-azaspiro[3.3]heptan-2-yl)prop-2-en-1-one ≥98%
Catalog Number:
(77625-268)
Supplier:
AMBEED, INC
Description:
(2S,4R)-1-((S)-2-(4-Aminobutanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride ≥95%
Supplier:
Strem Chemicals Inc
Description:
CAS #: 350683-75-9. Size: 0.5g.
Catalog Number:
(75788-874)
Supplier:
Prosci
Description:
Interleukin-33 (IL-33) was initially discovered as a nuclear factor NF-HEV abundantly expressed in high endothelial venules. It is a 30-32 kD pro-inflammatory protein with intracellular and extracellular activities and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 is highly and selectively expressed by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyers's patches, and lymph nodes. It contains a bipartite nuclear localization signal at the C-terminus, and is targeted to the nucleus when ectopically expressed in human umbilical vein endothelial cells (HUVECs) and HeLa cells. The C-terminal fragment, corresponding to mature IL-33, binds and triggers signaling. IL-33 mediates its biological effects via Toll-interleukin 1 (IL-1) receptor (TIR) domain-containing receptor ST2, activates NF-kappaB and MAP kinases, and drives production of T(H)2-associated cytokines from in vitro polarized T(H)2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs. Human IL-33 is 270 amino acids in length.
Supplier:
AMBEED, INC
Description:
(R)-2-Amino-3,3-dimethylbutan-1-ol, Purity: 97%, CAS Number: 112245-09-7, Appearance: Liquid or Solid or Semi-solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 250mg
Supplier:
Matrix Scientific
Description:
MF=C8H4CLFN2 MW=182.59 CAS=55687-33-7 MDL=MFCD09999192 1G
Supplier:
Matrix Scientific
Description:
MF=C21H38NNAO3 MW=375.53 CAS=58725-33-0 MDL=MFCD09751056 250MG
Supplier:
Adipogen
Description:
Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL-1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 (MAPK3) / ERK2 (MAPK1), p38 (MAPK14) and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases and sepsis. IL-33 facilitates Treg expansion in vitro and in vivo. Recently, IL-33 has been involved in adipocyte differentiation. The biological activity of IL-33 at its receptor ST2 is rapidly terminated in the extracellular environment by its oxidation (formation of two disulfide bridges), resulting in an extensive conformational change that disrupts the ST2 binding site. Mutations at amino acids C208S/C232S protect IL-33 from oxidation and increase its activity.
Supplier:
Matrix Scientific
Description:
MF=C5H7NO2 MW=113.12 CAS=39201-33-7 MDL=MFCD00218781 1G
Supplier:
Matrix Scientific
Description:
MF=C12H10N2O3 MW=230.23 Cas=6149-33-3 MDL=MFCD00060609 1G
Supplier:
Matrix Scientific
Description:
MF=C9H11NO MW=149.19 CAS=58196-33-1 MDL=MFCD08063887 5G
Catalog Number:
(77747-009)
Supplier:
AMBEED, INC
Description:
(S)-3,3'-Bis(10-phenyl-9-anthracenyl)-1,1'-binaphthyl-2,2'-diyl Hydrogenphosphate ≥98%
Catalog Number:
(100504-316)
Supplier:
Electron Microscopy Sciences
Description:
(2,2'-Di[p-nitrophenyl]-5,5'-di[p-thiocarbamylphenyl]-3,3'-[3,3'-dimethoxy-4,4'-biphenylene]ditetrazolium chloride)
Supplier:
AMBEED, INC
Description:
(R)-3,3'-Bis(9-phenanthrenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthyl HydrogenPhosphate, Purity: 98%, CAS Number: 934201-93-1, Appearance: Solid, Storage: Inert atmosphere, 2-8 C, Size: 1g
Catalog Number:
(77620-264)
Supplier:
AMBEED, INC
Description:
3,3-Bis(bromomethyl)-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine 98%
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