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Fall+Harnesses
Catalog Number:
(10287-532)
Supplier:
Bioss
Description:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors†because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Supplier:
Spectrum Chemicals
Description:
HEPES, Biological Buffer, Ultrapure is as it's name suggests, a buffering agent. It's a zwitterionic organic chemical that is one of the '20 Good's buffers. Because it's better at maintaining physiological pH despite changes in carbon dioxide, it is widely used in cell culture. It has a decrease of water dissociation with falling temperature, this is especially relevant when working at low temperatures as it maintains enzyme function and structure. That said, it is important when working with HEPES for that particular purpose to keep the HEPES-containing solution in darkness as much as possible
Catalog Number:
(10624-406)
Supplier:
Abnova
Description:
Mouse monoclonal antibody raised against a partial recombinant HARS.
Supplier:
Vetequip
Description:
Small bench-mounted units with unrestricted access are ideal for procedures that are difficult to perform in a fume hood or cabinet. The downdraft action takes the contaminated air away from the operator. An audible alarm sounds when the airflow falls to an unacceptable level. Clean air recirculates into the room, eliminating ducting and installation costs.
Catalog Number:
(76107-462)
Supplier:
Bioss
Description:
RENBP is a 427 amino acid protein that is a proteinaceous renin inhibitor. In inhibiting renin, RENBP forms a complex with it; a high molecular weight renin. RENBP contains a leucine zipper domain, which is essential for its dimerization with renin. RENBP can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Sequences of porcine, human and rat renin-binding proteins are highly homologous. The RENBP gene is conserved in dog, mouse, rat and zebrafish, and maps to human chromosome Xq28 between DXS52 and G6PD. Rat Renbp is located on chromosome X at Xq37 close to marker DXWox3 and falls outside the BP QTL regions on chromosome X.
Catalog Number:
(77699-682)
Supplier:
AFG BIOSCIENCE LLC
Description:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:20000
Catalog Number:
(10073-226)
Supplier:
Prosci
Description:
Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors.
Catalog Number:
(10588-318)
Supplier:
Abnova
Description:
HARS MaxPab rabbit polyclonal antibody (D01), Rabbit polyclonal antibody raised against a full-length human HARS protein, Size: 100ul
Supplier:
Thermo Fisher Scientific
Description:
Streamline daily pipetting. Thermo Scientific™ F1-ClipTip™ Fixed Volume Single Channel Pipettes feature innovative ClipTip interlocking technology which ensures a complete seal on every channel with minimal tip attachment and ejection force.
Catalog Number:
(10558-120)
Supplier:
Abnova
Description:
Mouse polyclonal antibody raised against a full-length human HARS protein.
Supplier:
Thermo Fisher Scientific
Description:
ClipTip technology locks tips firmly in place and ensures a complete seal on every channel with minimal tip attachment and ejection forces using Thermo Scientific™ F1-ClipTip™ Multichannel pipettes.
Supplier:
HexArmor
Description:
The AG10009S offers industrial puncture protection over the entire forearm with a spandex wrist insert and thumbhole. No more snags, punctures, abrasions, or cuts to the forearm with this unique product.
Catalog Number:
(10287-534)
Supplier:
Bioss
Description:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors†because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Catalog Number:
(10388-162)
Supplier:
Bioss
Description:
Ubiquitin like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg12 and Hub1. Proteins of the second class include Parkin, RAD23 and DSK2, are designated ubiquitin domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not proteolytically processed or conjugated to other proteins. Rub1 and the corresponding human homolog NEDD8 are activated by the E1 ubiquitin activating enzyme UBA2, that forms isopeptide linkages between thio esters. NEDD8 shows 80% homology to ubiquitin. The best known targets of Rub1 modification are members of the cullin family. Cullins are subunits of an E3 ubiquitin ligase complex called the Skp1 /Cul1/Cdc53 F box (SCF). The SCF promotes transfer of ubiquitin from a ubiquitin conjugating enzyme (E2) to the target protein. Rub1 modification may regulate SCF function or localization.
Catalog Number:
(77438-982)
Supplier:
Bioss
Description:
Anti-HARS Rabbit Polyclonal Antibody
Catalog Number:
(103359-728)
Supplier:
Novus Biologicals
Description:
The Caspase-8 Antibody (90A992) from Novus Biologicals is a mouse monoclonal antibody to Caspase-8. This antibody reacts with human, primate. The Caspase-8 Antibody (90A992) has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry-Paraffin, CyTOF-ready.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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