Fmoc-D-Lys(Fmoc)-OH
Catalog Number:
(10033-576)
Supplier:
Enzo Life Sciences
Description:
The SIRT5 Fluorometric Drug Discovery Kit is a sensitive fluorometric assay is designed to measure the lysyl desuccinylase activity of the recombinant human SIRT5.
Catalog Number:
(10165-456)
Supplier:
Genetex
Description:
Rat monoclonal antibody [FD441.8] to CD11
Catalog Number:
(10164-442)
Supplier:
Genetex
Description:
Rabbit polyclonal antibody to CD8
Supplier:
Sino Biological
Description:
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD5 (rM CD5; Catalog#50403-M08H; NP_031676.3; Met1-Pro371) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Catalog Number:
(76119-010)
Supplier:
Bioss
Description:
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
Catalog Number:
(76119-008)
Supplier:
Bioss
Description:
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
Catalog Number:
(103621-556)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human HPRG (NP_000403.1) (Met 1-Lys 525) with a C-terminal polyhistidine tag was expressed.
Catalog Number:
(103621-372)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the native human SCYE1 (NP_004748.2) (Ala 2-Lys 312) was expressed, with a polyhistide tag at the N-terminus.
Catalog Number:
(10315-890)
Supplier:
Bioss
Description:
E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation. Negatively regulates the suppressive function of regulatory T-cells (Treg) during inflammation by mediating the ubiquitination and degradation of FOXP3 in a HSPA1A/B-dependent manner.
Catalog Number:
(103621-142)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the extracellular domain of human IL20Rα isoform 1 (NP_055247.3) (Met 1-Lys 250) was fused with a polyhistidine tag at the C-terminus.
Catalog Number:
(103623-944)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human S100A4 (NP_002952.1) (Met 1-Lys 101) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Supplier:
Sino Biological
Description:
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD5 (rM CD5; Catalog#50403-M08H; NP_031676.3; Met1-Pro371) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Catalog Number:
(103623-962)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human Decorin (NP_001911.1) (Met 1-Lys 359) was expressed, with a polyhistidine tag at the C-terminus.
Catalog Number:
(10102-718)
Supplier:
Prosci
Description:
CHFR is an E3 ubiquitin-protein ligase required to transiently arrest cells in early prophase when they are exposed to microtubule poisons. It acts in early prophase before chromosome condensation, when the centrosome moves apart from each other along the periphery of the nucleus. CHFR probably promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress. This suggests that it may be involved in signaling the presence of mitotic stress caused by microtubule poisons.
Catalog Number:
(103621-054)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the extracellular domain of human IFNAR2 isoform a (NP_997468.1) (Met 1-Lys 243) was expressed, fused with a polyhistidine tag at the C-terminus.
Catalog Number:
(103008-544)
Supplier:
Anaspec Inc
Description:
This peptide is histone H4 (1-21), acetylated at lysine 12. The N-terminus contains a C-terminus GG linker followed by a biotinylated lysine. The acetylation of histone H4 plays a crucial role in structural changes that amplifies the binding of transcription factors to their recognition sites within the nucleosomes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:Ac-SGRGKGGKGLG-K(Ac)-GGAKRHRKV-GGK(Biotin) MW:2644.1 Da % peak area by HPLC:95 Storage condition:-20° C
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