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GSK-J4+hydrochloride
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GSK-J4+hydrochloride
Supplier:
AMBEED, INC
Description:
Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoate hydrochloride, Purity: 98%, CAS Number: 1797983-09-5, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 25mg
Supplier:
AMBEED, INC
Description:
GSK-484 hydrochloride ≥98%
Supplier:
AMBEED, INC
Description:
N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl)oxy)phenyl)-4-(2-morpholinoethoxy)benzamide hydrochloride, Purity: 98%, CAS Number: 2095432-71-4, Appearance: White to off-white solid, Storage: Inert atmosphere, 2-8 C, Size: 5mg
Supplier:
Adipogen
Description:
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
Supplier:
Adipogen
Description:
Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils.
Catalog Number:
(103918-882)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the Hepatitis C virus (HCV)(serotype 1b,isolate HC-J4E) E (AAC15723.1)(Glu384-Glu661) was expressed with a polyhistidine tag at the C-terminus.
Catalog Number:
(103664-072)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the envelope glycoprotein E1 of Hepatitis C virus (subtype 1b, strain HC-J4) (AAC15725.1) (Tyr192-Ile340) was expressed with a polyhistidine tag at the N-terminus.
Supplier:
Anaspec Inc
Description:
NS3 protease of hepatitis C virus (HCV), located on the N-terminal domain of HCV NS3, is responsible for the cleavage at the NS3/NS4A, NS4A/NS4B, NS4B/NS5A, and NS5A/NS5B sites of the nonstructural protein. The HCV NS3 is a chymotrypsin-like serine protease. It requires a cofactor, a 54 amino acid NS4 protein, to reach its optimal activity. The X-ray crystal structure studies show that NS3 forms a tight non-covalent complex with NS4. The NS3/4A protease is essential for viral replication and the formation of infectious viral particles, and thus has been considered as one of the most attractive targets for anti-HCV therapy.
The recombinant HCV NS3/4A protease (genotype 1b, strain: HC-J4; NCBI Accession: AF054247) was expressed in E. Coli. HCV NS3/4A protease is a 217 amino acid fusion protein (22.7 kDa) with NS4A co-factor fused to the N-terminus of NS3 protease domain. Therefore, HCV NS3/4A protease is in active form and the pre-activation by pep4A or pep4AK is not necessary. 5-20 ng of HCV NS3/4A protease is sufficient for FRET-based activity assays (SensoLyte® HCV protease assay).
Supplier:
Enzo Life Sciences
Description:
Potent inhibitor of GSK-3 ATP-binding site.
Catalog Number:
(AAJ64554-MA)
Supplier:
Thermo Scientific Chemicals
Description:
A cell-permeable, potent, and selective inhibitor of GSK-3beta
Catalog Number:
(76003-038)
Supplier:
Enzo Life Sciences
Description:
Cell-permeable, potent and selective GSK-3β inhibitor.
Supplier:
AMBEED, INC
Description:
4-Hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide, Purity: 98%, CAS Number: 101574-65-6, Appearance: Form: solid, Storage: Inert atmosphere, 2-8 C, Size: 1mg
Supplier:
AMBEED, INC
Description:
GSK-1059615 ≥98%
Supplier:
AMBEED, INC
Description:
N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine, Purity: 99+%, CAS Number: 1346546-69-7, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 5MG
Supplier:
AMBEED, INC
Description:
GSK-961081 98+%
Supplier:
AMBEED, INC
Description:
1-(4-Methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea, Purity: 98%, CAS Number: 487021-52-3, Appearance: Form: solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 10mg
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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