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Gal[236Bn]beta(1-4)Glc[236Bn]-beta-MP
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Gal[236Bn]beta(1-4)Glc[236Bn]-beta-MP
Catalog Number:
(76194-482)
Supplier:
Prosci
Description:
Beta Catenin is a dual function protein, regulating the coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. b-Catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. b-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]
Catalog Number:
(10416-008)
Supplier:
Bioss
Description:
The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit (95 kDa) possesses a single transmembrane domain, whereas the alpha subunit (135 kDa) is completely extracellular. The insulin receptor exhibits receptor tyrosine kinase (RTK) activity. RTKs are single pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the gamma phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that affect cell proliferation, differentiation, migration and metabolism.Included in this large protein family are the insulin receptor and the receptors for growth factors such as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. Receptor activation occurs through ligand binding, which facilitates receptor dimerization and autophosphorylation of specific tyrosine residues in the cytoplasmic portion. The interaction of insulin with the alpha subunit of the insulin receptor activates the protein tyrosine kinase of the beta subunit, which then undergoes an autophosphorylation that increases its tyrosine kinase activity. Three adapter proteins, IRS1, IRS2 and Shc, become phosphorylated on tyrosine residues following insulin receptor activation. These three phosphorylated proteins then interact with SH2 domain containing signaling proteins.
Supplier:
Spectrum Chemicals
Description:
CHLOROBUTANOL, HEMIHYDRATE, NF is a chemical sedative hypnotic, preservative and weak local anesthetic. It is also a low level antibacterial and antifungal. In water it is known to retain it's antimicrobial activity at 0.05%. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Catalog Number:
(76100-614)
Supplier:
Bioss
Description:
JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.
Catalog Number:
(76710-912)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse Laminin Subunit beta-1(LAMB1) ELISA Kit
Supplier:
Tonbo Biosciences
Description:
The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.</p><p>The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.
Catalog Number:
(103230-824)
Supplier:
Novus Biologicals
Description:
TGF-beta RI/ALK-5, Polyclonal Antibody, Host: Goat, Species Reactivity: Mouse, Isotype: IgG, Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF- beta RI/ALK-5, Synonyms: AAT5, 53kDa, Application: WB, Size: 100UG
Catalog Number:
(77694-796)
Supplier:
LGC STANDARDS
Description:
4-Methylumbelliferyl 6-Thio-palmitate-Beta-D-glucopyranoside, TRC, LGC Standards
Catalog Number:
(77519-266)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human ITGb2 (Integrin Beta 2) ELISA Kit
Catalog Number:
(77527-534)
Supplier:
AFG BIOSCIENCE LLC
Description:
Cattle ITGb2 (Integrin Beta 2) ELISA Kit
Catalog Number:
(76713-222)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat Interleukin-36 beta (IL1F8) ELISA Kit
Catalog Number:
(76699-308)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse Resistin-like beta(RETNLB) ELISA Kit
Supplier:
AOB CHEM USA
Description:
1-(2-Bromoethoxy)-3-chlorobenzene ≥97%
Catalog Number:
(102512-424)
Supplier:
Adipogen
Description:
Human CD51 is an integrin alpha v chain which can associate with five different integrin beta chains to form various adhesion molecules. The alpha v beta 3 integrin complex binds vitronectin at the RGD sequence and also can bind to fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen.
Catalog Number:
(102512-422)
Supplier:
Adipogen
Description:
Human CD51 is an integrin alpha v chain which can associate with five different integrin beta chains to form various adhesion molecules. The alpha v beta 3 integrin complex binds vitronectin at the RGD sequence and also can bind to fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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