Gal[236Bn]beta(1-4)Glc[236Bn]-beta-MP
Catalog Number:
(77525-076)
Supplier:
AFG BIOSCIENCE LLC
Description:
Simian TGFb1 (Transforming Growth Factor Beta 1) ELISA Kit
Catalog Number:
(10250-474)
Supplier:
Bioss
Description:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Catalog Number:
(76704-918)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Regenerating Islet-Derived Protein 3- beta(REG3B) ELISA Kit
Catalog Number:
(76707-828)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Epididymal secretory Protein E3-beta(FAM12B) ELISA Kit
Catalog Number:
(76705-932)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse Interleukin-2 Receptor Subunit beta (Il2rb/CD122) ELISA Kit
Catalog Number:
(10300-356)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Catalog Number:
(10300-350)
Supplier:
Bioss
Description:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
Catalog Number:
(77519-278)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human ETFb (Electron Transfer Flavoprotein Beta Polypeptide) ELISA Kit
Catalog Number:
(76715-072)
Supplier:
AFG BIOSCIENCE LLC
Description:
Human Transforming Growth Factor, beta 2 (TGFB2) AutoAntibody ELISA Kit
Catalog Number:
(77518-080)
Supplier:
AFG BIOSCIENCE LLC
Description:
Rat ATP1b3 (ATPase, Na+/K+ Transporting Beta 3 Polypeptide) ELISA Kit
Catalog Number:
(10481-390)
Supplier:
Bioss
Description:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Catalog Number:
(76107-406)
Supplier:
Bioss
Description:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Catalog Number:
(75789-820)
Supplier:
Prosci
Description:
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
Catalog Number:
(76714-010)
Supplier:
AFG BIOSCIENCE LLC
Description:
Mouse Interleukin-10 Receptor Subunit beta(IL10RB) ELISA Kit
Catalog Number:
(10281-660)
Supplier:
Bioss
Description:
14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
Catalog Number:
(102110-764)
Supplier:
Novus Biologicals
Description:
The PA28 Activator beta Subunit / PSME2 Antibody from Novus Biologicals is a goat polyclonal antibody to PA28 Activator beta Subunit / PSME2. This antibody reacts with human. The PA28 Activator beta Subunit / PSME2 Antibody has been validated for the following applications: Western Blot, Peptide ELISA.
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