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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(76080-472)
Supplier:
Bioss
Description:
MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family, (MAP kinase kinase family). It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, and not with another MAP kinase like P38. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). It is not phosphorylated by RAFA, RAFB or RAFC and it may interact with GTPases such as CDC42. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. MEK5 is expressed in many adult tissues and is most abundant in heart and skeletal muscle.
Supplier:
Sino Biological
Description:
A DNA sequence encoding the mature form of mouse IL1β (P10749) (Val 118-Ser 269) was expressed, with an initial Met at the C-terminus.
Supplier:
Bachem Americas
Description:
This fluorogenic HIV-1 protease substrate consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH₂-termini. The γ-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.
Catalog Number:
(10478-982)
Supplier:
Bioss
Description:
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Catalog Number:
(76101-380)
Supplier:
Bioss
Description:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Catalog Number:
(10473-440)
Supplier:
Bioss
Description:
Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.
Catalog Number:
(103624-328)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the <i>E.Coli</i> ssPA (P0ACA3) (Met 1-Ser 212) was expressed, with a polyhistidine tag at the N-terminus.
Catalog Number:
(103623-132)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human FABP1 (NP_001434.1) (Ser 2-Ile 127) was expressed, with a polyhistide tag at the N-terminus.
Catalog Number:
(80054-792)
Supplier:
MilliporeSigma
Description:
A highly specific, cell-permeable, and irreversible inhibitor of caspases, including caspase-1, caspase-3, caspase-4, and caspase-7
Catalog Number:
(10070-302)
Supplier:
Prosci
Description:
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
Catalog Number:
(10474-790)
Supplier:
Bioss
Description:
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
Catalog Number:
(10473-558)
Supplier:
Bioss
Description:
The function of ADCK1 is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
Catalog Number:
(103621-072)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the amino acid sequence (Cys 198-Ser 462) of human SHH (Q15465), that is Sonic hedgehog protein C-product, was fused with a polyhistidine tag at the C-terminus and a signal peptide at the N-terminus.
Catalog Number:
(RL200501E71)
Supplier:
Rockland Immunochemical
Description:
AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases).
Catalog Number:
(RL200301E75S)
Supplier:
Rockland Immunochemical
Description:
AKT3 Antibody detects AKT3 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases).
Catalog Number:
(10333-780)
Supplier:
Bioss
Description:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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