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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Catalog Number:
(10325-946)
Supplier:
Bioss
Description:
Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2). The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75'. Phosphorylates adenylyl cyclases: ADCY2, ADCY5 and ADCY6, resulting in their activation. Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity. Phosphorylates TNNT2/cardiac muscle troponin T. Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), apoptosis (MAP3K5/ASK1 and STK3/MST2), proliferation and angiogenesis (RB1). Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death. Regulates Rho signaling and migration, and is required for normal wound healing. Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, which induces down-regulation of OCLN. Restricts caspase activation in response to selected stimuli, notably Fas stimulation, pathogen-mediated macrophage apoptosis, and erythroid differentiation.
Supplier:
Bachem Americas
Description:
LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).
Supplier:
Promega Corporation
Description:
Recombinant full-length human GRK5 was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family.
Catalog Number:
(PAV4067)
Supplier:
Promega Corporation
Description:
Recombinant human HIPK1 (156-555) was expressed in Sf9 cells using an N-terminal GST tag. HIPK1 or homeodomain-interacting protein kinase 1 is a ser/thr protein kinase and a member of the HIPK family.
Catalog Number:
(103623-244)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human PA2G4 (Q9UQ80) (Ser 2-Asp 394) was expressed, with a polyhistide tag at the N-terminus.
Catalog Number:
(103679-488)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human PAPPA2 mature form (NP_064714.2) corresponding to amino acid (Ser 234-Cys 1396) was expressed， with a carboxy-terminal polyhistidine tag.
Supplier:
ACROBIOSYSTEMS INC MS
Description:
SARS-CoV-2 (COVID-19) S1 protein NTD, His Tag, ACROBiosystems
Supplier:
MilliporeSigma
Description:
TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride), Molecular Biology Grade
Supplier:
AMBEED, INC
Description:
H-Chg-OtBu.HCl, Purity: 97%, CAS Number: 213475-52-6, Appearance: Colorless or white to off-white solid or liquid, Storage: Sealed in dry, Room Temperature, Size: 10G
Catalog Number:
(103633-868)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the N-terminal fragment (Ser 2-Lys 246) of human NRG1 isoform beta1 (Q02297-6) was fused with the Fc region of human IgG1 at the N-terminus.
Catalog Number:
(10333-784)
Supplier:
Bioss
Description:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Catalog Number:
(10333-776)
Supplier:
Bioss
Description:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Catalog Number:
(103666-084)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the extracellular domain of canine IL5 (NP_001006951.1) (Met 1-Ser 134) was expressed, with a polyhistidine tag at the C-terminus.
Catalog Number:
(10408-516)
Supplier:
Bioss
Description:
This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production. It probably has a preference for proteins phosphorylated on Ser and/or Thr residues compared to phosphorylation on Tyr residues. It is likely to be involved in the regulation of insulin secretion in pancreatic beta cells.
Catalog Number:
(103665-504)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the mouse PTPN2 (Q06180-1) (Ser 2-Asn 314) was fused with a polyhistidine tag at the N-terminus.
Catalog Number:
(103613-922)
Supplier:
Sino Biological
Description:
A DNA sequence encoding the human SUMO1 (AAH66306.1) (Ser 2-Val 101) was expressed, with a polyhistide tag at the N-terminus.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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