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4-(2-Oxopropyl)benzoic+acid
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4-(2-Oxopropyl)benzoic+acid
Supplier:
MilliporeSigma
Description:
Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs
Supplier:
Thermo Scientific Chemicals
Description:
250mg CAS: 270596-46-8, MDL: MFCD01861006
Catalog Number:
(101942-804)
Supplier:
Matrix Scientific
Description:
MF=C5Hcl2N3S MW=206.05 Cas=13479-88-4 500Mg
Catalog Number:
(TS38870-1000)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Hydrochloric acid 1 M in ethyl acetate
Catalog Number:
(10258-976)
Supplier:
Bioss
Description:
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family. Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis, CDKL5 is thought to play a role in cell cycle regulation. Defects in CDKL5 are a cause of several disorders, such as X-linked infantile spasm syndrome and Rett syndrome.
Catalog Number:
(101831-334)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 031258-500MG , MDL Number: MFCD07375466
Catalog Number:
(75933-434)
Supplier:
Rockland Immunochemical
Description:
ULK3 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK3, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK4, is highly conserved among eukaryotes (3). ULK3 has been shown to be a positive regulator of the Hedgehog signaling pathway by enhancing GLI1 and GLI2 transcriptional activity (4). Furthermore, ULK3 can also interact with SUFU, a protein required for the negative regulation of GLI proteins; this interaction blocks the autophosphorylation of ULK3 and blocks its ability to regulate the GLI proteins (5).
Catalog Number:
(10801-850)
Supplier:
Rockland Immunochemical
Description:
AKT1 is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and RAC (Related to A and C kinases). AKT is a key regulator of many signal transduction pathways, and it exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. AKT1 mutant (T308 / S473A) recombinant protein is ideal for investigators involved in Cell Signaling, Neuroscience and Signal Transduction research.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Azetidine hydrochloride 97%
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Trazodone-d6 HCl
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Miglustat-d9 HCl
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Quinapril-d5 HCl
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Pantoprazole Impurity 6 HCl
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Pinaverium Impurity 6 HCl
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Phenylephrine-d3 HCl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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