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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Supplier:
BeanTown Chemical
Description:
CAS: 19524-06-2; EC No: 243-128-4; MDL No: MFCD00012828
Crystalline; Molecular Formula: C5H4BrN·HCl ; MW: 194.46
Melting Point: 270° (decomposes)
Hygroscopic
Catalog Number:
(AAH27547-03)
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 75098-40-7, MDL: MFCD07777098
Supplier:
AMBEED, INC
Description:
(R)-N2,N2,6-Trimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride 98%
Catalog Number:
(100503-800)
Supplier:
Electron Microscopy Sciences
Description:
A non-carcinogenic substitute for DAB and DAB-HCl.
Supplier:
AMBEED, INC
Description:
Bis(2-bromobenzyl)amine hydrochloride 95%
Catalog Number:
(76082-762)
Supplier:
Bioss
Description:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Supplier:
ALADDIN SCIENTIFIC
Description:
2-Aminothiazole-5-carbaldehyde hydrochloride ≥95%
Catalog Number:
(10799-926)
Supplier:
Rockland Immunochemical
Description:
AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as AKT1, Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT Antibody is ideal for investigators involved in Cell Signaling, Cancer, Neuroscience, Signal Transduction research.
Catalog Number:
(10799-932)
Supplier:
Rockland Immunochemical
Description:
AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Catalog Number:
(10412-246)
Supplier:
Bioss
Description:
Chk2 is a serine/threonine kinase involved in the control of cell cycle checkpoints, and may also participate in transduction of the DNA damage and replicational stress signals. Chk2 is the mammalian ortholog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine and threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50 and Thr68) followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. Indeed, after DNA damage by ionizing radiation (IR), UV irradiation or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 on residues Thr383 and Thr387 in the activation loop of the kinase domain. Chk2 inhibits CDC25C phosphatase by phosphorylating it on Ser-216, preventing the entry into mitosis. This kinase may have a role in meiosis as well. Kinase activity is up regulated by autophosphorylation and the protein is rapidly phosphorylated in response to DNA damage and to replication block.
Supplier:
Thermo Scientific Chemicals
Description:
L-Isoleucine ethyl ester hydrochloride, Purity: 98%, CAS Number: 56782-52-6, Molecular Formula: C8H17NO2.HCl, Color: White, Form: Powder, Synonym: Ethyl L-isoleucinate hydrochloride H-Ile-Oe.HCl, 25G
Catalog Number:
(101938-120)
Supplier:
Matrix Scientific
Description:
Ethyl Azetidine-3-Carboxylate Hydrochloride, MF=C6H12Clno2 MW=165.62 CAS: 405090-31-5 1G
Supplier:
AMBEED, INC
Description:
N-Boc-1,3-propanediamine 97%
Supplier:
Welch Vacuum
Description:
Corrosive gases, such as HCl, HBr, Br2, Cl2, and F3CCO2H, are commonly used for peptide chemistry, molecular biology, and biochemistry applications
Supplier:
AMBEED, INC
Description:
Ethyl azetidine-3-carboxylate hydrochloride, Purity: 97%, CAS Number: 405090-31-5, Appearance: Solid, Storage: Inert atmosphere, 2-8C, Size: 10G
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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