H-d-Ser(tBu)-OMe·HCl
Supplier:
Thermo Scientific Chemicals
Description:
Nuclear counterstain useful in pH range 6.8 - 8.0.
Supplier:
HCL Label
Description:
These ready-made adhesive vinyl labels comply with the updated OSHA HazCom 'secondary container' labeling requirements.
Supplier:
AMBEED, INC
Description:
2-(Trifluoromethyl)phenylhydrazinium chloride 98%
Supplier:
Thermo Scientific Chemicals
Description:
Ethyl 2-amidinoacetate hydrochloride, Purity: 95%, Cas Number: 57508-48-2, Molecular formula: C5H10N2O2.HCl, Color: White, Form: Powder, Synonym: Ethyl 3-amino-3-iminopropionate hydrochloride, 3-Amino-3-iminopropionic acid ethyl ester hydrochlorid, 5G
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
(R)-(−)-Phenylephrine hydrochloride 99%
Catalog Number:
(77170-050)
Supplier:
AMBEED, INC
Description:
2,6-Dichloro-5-iodonicotinonitrile, Purity: 95%, CAS Number: 1353087-61-2, Appearance: Solid, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 250mg
Supplier:
AMBEED, INC
Description:
4,6-Dichloropyridazine-3-carbonitrile, Purity: 95%, CAS Number: 35857-90-0, Appearance: Solid or liquid, Storage: Inert atmosphere, 2-8C, Size: 100MG
Supplier:
AMBEED, INC
Description:
Bestatin hydrochloride ([S-(R*,S*)]-N-(3-amino-2-hydroxy-4-phenylbutyroyl)-L-leucine hydrochloride) 98%
Supplier:
AMBEED, INC
Description:
(R)-N2,N2,6-Trimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine hydrochloride 98%
Catalog Number:
(76082-762)
Supplier:
Bioss
Description:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Supplier:
BeanTown Chemical
Description:
CAS: 72830-09-2; EC No: 416-440-5; MDL No: MFCD02181083
UN No: UN3077; Haz Class: 9; Packing Group: III
Solid; Molecular Formula: C8H11Cl2NO2; MW: 224.08
Melting Point: 155° (decomposes)
Supplier:
TCI America
Description:
CAS Number: 7179-49-9
MDL Number: MFCD00167245 Molecular Formula: C18H34N2O6S Molecular Weight: 443.00 Purity/Analysis Method: >98.0% (T) Form: Crystal Melting point (°C): 154 Specific rotation [a]20/D: 137 deg (C=1, H2O)
Catalog Number:
(10412-246)
Supplier:
Bioss
Description:
Chk2 is a serine/threonine kinase involved in the control of cell cycle checkpoints, and may also participate in transduction of the DNA damage and replicational stress signals. Chk2 is the mammalian ortholog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine and threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50 and Thr68) followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. Indeed, after DNA damage by ionizing radiation (IR), UV irradiation or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 on residues Thr383 and Thr387 in the activation loop of the kinase domain. Chk2 inhibits CDC25C phosphatase by phosphorylating it on Ser-216, preventing the entry into mitosis. This kinase may have a role in meiosis as well. Kinase activity is up regulated by autophosphorylation and the protein is rapidly phosphorylated in response to DNA damage and to replication block.
Catalog Number:
(AAH27770-03)
Supplier:
Thermo Scientific Chemicals
Description:
1g CAS: 426844-51-1, MDL: MFCD06797014
Supplier:
Thermo Scientific Chemicals
Description:
50% v/v Aqueous Solution,UN1789,Liquid,DANGER: CORROSIVE, burns skin and eyes,1L,4L,CORROSIVE,NO CAN FOR GROUND SHIPMENT
Supplier:
TCI America
Description:
CAS Number: 2924-15-4
MDL Number: MFCD00012927 Molecular Formula: C6H7FN2 Molecular Weight: 162.59 Purity/Analysis Method: >97.0% (T) Form: Crystal
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