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H-d-Ser(tBu)-OMe·HCl
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H-d-Ser(tBu)-OMe·HCl
Supplier:
Thermo Scientific Chemicals
Description:
Molecular Formula: Pt in 20% HCl
Physical Form: Liquid Odor: Characteristic UN No.: 1789 MDL No.: MFCD00011179
Supplier:
TCI America
Description:
CAS Number: 5022-65-1
MDL Number: MFCD00054315
Molecular Formula: C11H13N3O
Molecular Weight: 239.70
Purity/Analysis Method: <gt/>98.0% (HPLC,N)
Form: Crystal
Color: White
Melting point (°C): 250
Specific rotation [a]20/D: 25 deg (C=1, H2O)
Catalog Number:
(76078-794)
Supplier:
Bioss
Description:
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
N-α-Benzoyl-DL-arginine-4-nitroanilide hydrochloride 98%
Supplier:
TLC PHARMACEUTICAL STANDARD LTD
Description:
Pharmaceutical Standards, Cetirizine Sorbitol Ester Impurity HCl (Mixture of Diastereomers)
Catalog Number:
(77697-143)
Supplier:
LGC STANDARDS
Description:
Dimethylamylamine Hydrochloride (4-Methyl-2-hexanamine Hydrochloride; DMAA HCl), LoGiCal, LGC Standards
Supplier:
TCI America
Description:
n-Octylamine Hydrochloride, Purity: >98.0%(T), CAS Number: 142-95-0, Molecular Formula: C8H19N.HCl, Molecular Weight: 165.71, Synonyms: OACl, n-Octylammonium Chloride, Size: 5G
Catalog Number:
(77625-466)
Supplier:
AMBEED, INC
Description:
2-(2,6-Dioxopiperidin-3-yl)-5-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride ≥98%
Supplier:
ALADDIN SCIENTIFIC
Description:
An inhibitor of 1,4-dihydropyridine binding to L-type Ca2+ channels
Catalog Number:
(PAG1521)
Supplier:
Promega Corporation
Description:
Human Female Genomic DNA is purified and stored in 10mM Tris-HCl (pH 8.0), 1mM EDTA >90% of the DNA is longer than 50kb in size as measured by pulsed-field gel electrophoresis. The DNA is suitable for Southern blot hybridizations, genomic analysis (including PCR) and genomic library construction. Human Genomic DNA comes from multiple anonymous donors.
Catalog Number:
(EM8.41494.0001)
Catalog Number:
(10346-792)
Supplier:
Bioss
Description:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Supplier:
Ricca Chemical
Description:
1 mL = 10 mg Fe, 10,000 ppm Fe. (FeCl3*6H2O in dilute HCl). Container: Glass.
Catalog Number:
(10326-634)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades; isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.
Catalog Number:
(10412-260)
Supplier:
Bioss
Description:
Chk2 is a serine/threonine kinase involved in the control of cell cycle checkpoints, and may also participate in transduction of the DNA damage and replicational stress signals. Chk2 is the mammalian ortholog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine and threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50 and Thr68) followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. Indeed, after DNA damage by ionizing radiation (IR), UV irradiation or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 on residues Thr383 and Thr387 in the activation loop of the kinase domain. Chk2 inhibits CDC25C phosphatase by phosphorylating it on Ser-216, preventing the entry into mitosis. This kinase may have a role in meiosis as well. Kinase activity is up regulated by autophosphorylation and the protein is rapidly phosphorylated in response to DNA damage and to replication block.
Supplier:
Thermo Scientific Chemicals
Description:
Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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