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HAT+activator,+CTPB
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HAT+activator,+CTPB
Catalog Number:
(76483-778)
Supplier:
AAT BIOQUEST INC
Description:
Our Cell Meterâ„¢ assay kits are a set of tools for monitoring cell viability.
Catalog Number:
(H-3730.1000BA)
Supplier:
Bachem Americas
Description:
Porcine intestinal peptide which belongs to the glucagon-secretin family. It exhibits biological activities similar to vasoactive intestinal peptide (VIP) and secretin.
Catalog Number:
(10765-376)
Supplier:
Prosci
Description:
The NIB42 monoclonal antibody specifically reacts with human interferon gamma, a multifunctional cytokine that is produced mainly by activated T and NK cells. Interferon gamma has anti-viral and anti-parasitic properties and plays an important role in the activation, growth, and differentiation of macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-alpha, to inhibit proliferation of normal and transformed cells. The NIB42 antibody neutralizes IFN-gamma.
Catalog Number:
(76174-292)
Supplier:
Boster Biological Technology
Description:
Rabbit IgG polyclonal antibody for 5'-AMP-activated protein kinase subunit beta-1(PRKAB1) detection. Tested with WB in Human.
Catalog Number:
(10666-622)
Supplier:
Bioss
Description:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.
Catalog Number:
(89278-646)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to APAF1 (apoptotic peptidase activating factor 1) Purity: n/a Species Reactivity: Human Mouse Rat Tested Applications: WB Pkg Size: 1 ml
Catalog Number:
(76084-732)
Supplier:
Bioss
Description:
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to proinflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14.
Catalog Number:
(10757-478)
Supplier:
Biolegend
Description:
Ultra-LEAF™ Purified anti-mouse CD300a [TX41]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: FC, IP, Activ; Size: 100 μg
Supplier:
Shenandoah Biotechnology
Description:
Interferon-inducible T cell alpha chemoattractant (I-TAC), or CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. I-TAC gene expression is induced by interferons alpha (IFN-α), beta (IFN-β), and gamma (IFN-ɣ). I-TAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. I-TAC functions as a chemoattractant for interleukin 2 (IL-2)-activated T cells.
Catalog Number:
(10072-992)
Supplier:
Prosci
Description:
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant human GRO-gamma is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Supplier:
Shenandoah Biotechnology
Description:
Interferon-alpha 2a (IFN-α 2a) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α 2a. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α 2a variant differs from IFN-α 2b by one amino acid.
Catalog Number:
(10072-960)
Supplier:
Prosci
Description:
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Catalog Number:
(10764-654)
Supplier:
Prosci
Description:
CD45.2 Antibody, monoclonal, Host: Mouse, Species reactivity: Mouse, Isotype: IgG2a, kappa, Clone: 104, Conjugate: PE, Applications: Fluorescence-activated cell sorting
Catalog Number:
(10764-958)
Supplier:
Prosci
Description:
CD123 Antibody, monoclonal, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Clone: 6H6, Conjugate: PE, Applications: Fluorescence-activated cell sorting
Catalog Number:
(10464-718)
Supplier:
Bioss
Description:
Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
Catalog Number:
(10362-704)
Supplier:
Bioss
Description:
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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