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EAGLE MHC
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EAGLE MHC
Supplier:
BeanTown Chemical
Description:
CAS: 26759-46-6; EC No: 247-967-7; MDL No: MFCD00014904
Powder; Molecular Formula: C10H13NO4; MW: 211.22
Melting Point: 128-133°
Supplier:
AMBEED, INC
Description:
3,4-Dimethoxyphenylboronic acid pinacol ester 97%
Catalog Number:
(77936-512)
Supplier:
AOB CHEM USA
Description:
33-DICHLOROBENZOPHENONE 5G
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,4-Dimethoxybenzaldehyde 98%
Supplier:
AMBEED, INC
Description:
2,6-Dimethoxypyridine 98%
Catalog Number:
(102538-154)
Supplier:
Matrix Scientific
Description:
MF=C5H10BR2O2 MW=261.95 CAS=22094-18-4 MDL=MFCD00051792 100G
Catalog Number:
(TS30579-0010)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
2,6-Dimethoxybenzaldehyde 99%
Catalog Number:
(76078-178)
Supplier:
Bioss
Description:
Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR complex depends on the BTB domain-containing protein as the substrate recognition component. BCR(KLHL42) is involved in ubiquitination of KATNA1. BCR(SPOP) is involved in ubiquitination of BMI1/PCGF4, BRMS1, H2AFY and DAXX, GLI2 and GLI3. Can also form a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL; these complexes have lower ubiquitin ligase activity. BCR(KLHL9-KLHL13) controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. BCR(KLHL12) is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). BCR(KLHL3) acts as a regulator of ion transport in the distal nephron; by mediating ubiquitination of WNK4. The BCR(KLHL20) E3 ubiquitin ligase complex is involved in interferon response and anterograde Golgi to endosome transport: it mediates both ubiquitination leading to degradation and 'Lys-33'-linked ubiquitination (PubMed:20389280, PubMed:21840486, PubMed:21670212, PubMed:24768539).
Catalog Number:
(77904-922)
Supplier:
AOB CHEM USA
Description:
33-DIMETHYLBENZOPHENONE 500MG
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
3,5-Dimethoxybenzoic acid 99%
Catalog Number:
(AAJ62311-06)
Supplier:
Thermo Scientific Chemicals
Description:
Apoptosis inhibitor. Increases P-glycoprotein expression in hepatoma cells. Stain for heparin in mast cells
Supplier:
ALADDIN SCIENTIFIC
Description:
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Supplier:
AMBEED, INC
Description:
2,5-Dimethoxybenzaldehyde 98%
Catalog Number:
(77992-854)
Supplier:
LGC STANDARDS
Description:
RK 33 2.5MG
Supplier:
TCI America
Description:
CAS Number: 17715-69-4
MDL Number: MFCD00009844 Molecular Formula: C8H9BrO2 Molecular Weight: 217.06 Purity/Analysis Method: >97.0% (GC) Form: Crystal Boiling point (°C): 132 Flash Point (°C): 110 Freezing point (°C): 25
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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