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Indium(III)+phosphate
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Indium(III)+phosphate
Supplier:
BeanTown Chemical
Description:
CAS: 7440-74-6; EC No: 231-180-0; MDL No: MFCD00134048; RTECS: NL1050000
Solid; Molecular Formula: In; MW: 114.82
Melting Point: 156.6°; Boiling Point: 2072°
Density (g/mL): 7.3
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7440-74-6. Size: 25g.
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7440-74-6. Size: 25g.
Catalog Number:
(77436-688)
Supplier:
Bioss
Description:
Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. Nitric oxide synthase is expressed in liver, macrophages, hepatocytes, synoviocytes, stimulated glial cells and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOSâ‚‚).
Catalog Number:
(76084-286)
Supplier:
Bioss
Description:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP.
Catalog Number:
(BT122060-50G)
Supplier:
BeanTown Chemical
Description:
CAS: 7440-74-6; EC No: 231-180-0; MDL No: MFCD00134048; RTECS: NL1050000
Solid; Molecular Formula: In; MW: 114.82
Melting Point: 156.6°; Boiling Point: 2072°
Density (g/mL): 7.3
Supplier:
AMBEED, INC
Description:
Indium(I) iodide 98%
Supplier:
BeanTown Chemical
Description:
CAS: 7440-74-6; EC No: 231-180-0; MDL No: MFCD00134048; RTECS: NL1050000
Solid; Molecular Formula: In; MW: 114.82
Melting Point: 156.6°; Boiling Point: 2072°
Density (g/mL): 7.3
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is still displayed and you need assistance, please call us at 1-800-932-5000.
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